An Interventional, Comparative, Prospective Study to Determine Optimum Concentration of Intralesional Triamcinolone Acetonide in Treatment of Alopecia Areata

    October 2025 in “ Indian Dermatology Online Journal
    Dhurat Rachita, Sachin Madhavrao Chamle, Richa Sharma
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    TLDR 2.5 mg/ml of triamcinolone acetonide is more effective for treating alopecia areata.
    This study investigated the optimal concentration of intralesional triamcinolone acetonide for treating alopecia areata by comparing 1.25 mg/ml and 2.5 mg/ml concentrations in 35 patients with 70 alopecic patches. The results showed that 2.5 mg/ml was significantly more effective, with 62.8% of patches achieving more than 75% hair regrowth, compared to the 1.25 mg/ml concentration, where 74% of patches failed to show more than 50% regrowth. No adverse effects were reported, suggesting that 2.5 mg/ml is the minimal effective concentration for managing alopecia areata.
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