Chronic Graft-Versus-Host Disease: The Role of Dermatological Treatment

    January 2017 in “ Dermatology Review ”
    Magdalena Żychowska, Joanna Gruber-Kopczyńska, Małgorzata Tupikowska-Marzec, Joanna Maj
    TLDR Skin issues from chronic graft-versus-host disease greatly affect daily life, needing teamwork between blood and skin doctors.
    The document discussed chronic graft-versus-host disease (cGVHD), a common complication following allogeneic haematopoietic stem cell transplantation, affecting the skin in over 90% of cases. It presented a case of a 45-year-old male with cGVHD exhibiting various skin lesions, including hyperpigmented lichenoid eruptions, non-scarring alopecia, poikiloderma, and sclerodermatous lesions. The treatment involved phototherapy and intensive topical applications. The study concluded that skin lesions from cGVHD could significantly impact patients' daily lives, emphasizing the need for collaborative management between haematologists and dermatologists.
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