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    Glossary Chromatin

    complex of DNA and proteins in cell nuclei

    Chromatin is a complex of DNA and proteins found in the nucleus of cells. It packages the long DNA molecules into a more compact, dense shape, allowing for efficient regulation of gene expression and DNA replication. For a layperson, think of it as the way your genetic material is neatly organized and stored in your cells.

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    1. Genome-wide Maps of Histone Modifications Unwind In Vivo Chromatin States of the Hair Follicle Lineage Cell stem cell · 2011 · 191 citations
    2. ATP-dependent chromatin remodeling during mammalian development Development · 2016 · 182 citations
    3. Roles of <i>jumonji</i> and <i>jumonji</i> family genes in chromatin regulation and development Developmental Dynamics · 2006 · 178 citations
    4. Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition Cell stem cell · 2016 · 174 citations
    5. p63 regulates <i>Satb1</i> to control tissue-specific chromatin remodeling during development of the epidermis The Journal of Cell Biology · 2011 · 166 citations
    6. Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression Cell stem cell · 2018 · 85 citations
    7. Live imaging reveals chromatin compaction transitions and dynamic transcriptional bursting during stem cell differentiation in vivo eLife · 2023 · 23 citations
    8. Hair Follicle Stem Cell Faith Is Dependent on Chromatin Remodeling Capacity Following Low-Dose Radiation Stem cells · 2017 · 13 citations
    9. Lineage commitment of dermal fibroblast progenitors is controlled by Kdm6b‐mediated chromatin demethylation The EMBO Journal · 2023 · 10 citations
    10. Tailored chromatin modulation to promote tissue regeneration Seminars in Cell & Developmental Biology · 2019 · 10 citations
    11. Single cell analysis of transcriptome and open chromatin reveals the dynamics of hair follicle stem cell aging Frontiers in Aging · 2023 · 3 citations
    12. DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation Science advances · 2023 · 3 citations
    13. How a Bird Gets Its Feathers: Insights from Chromatin Looping Developmental Cell · 2020 · 3 citations
    14. Linking chromatin dynamics, cell fate plasticity, and tissue homeostasis in adult mouse hair follicle stem cells Endogenous locus-driven H-Ras G12V expression induces senescence-like phenotype in primary fibroblasts of the Costello syndrome mouse model · 2017 · 3 citations
    15. Single-cell chromatin landscapes of mouse skin development Scientific Data · 2022 · 2 citations
    16. Second International Symposium—Epigenetic Regulation of Skin Regeneration and Aging: From Chromatin Biology towards the Understanding of Epigenetic Basis of Skin Diseases 2017 · 2 citations
    17. Lineage Commitment of Dermal Fibroblast Progenitors is Mediated by Chromatin De-repression bioRxiv (Cold Spring Harbor Laboratory) · 2023 · 1 citations
    18. States and Fates of Skin Fibroblasts Revealed through Chromatin Accessibility Journal of Investigative Dermatology · 2022
    19. 1435 Dynamic morphogen-p63 chromatin interactions that guide epigenetic changes and p63 activity in surface ectoderm commitment Journal of Investigative Dermatology · 2018
    20. Linking Morphogen and Chromatin in the Hair Follicle Developmental Cell · 2013
    21. TTNPB Promotes Human Pluripotent Stem Cell‐to‐Neural Stem Cell Transition via Modulation of Chromatin Accessibility and the S‐(5′‐adenosyl)‐L‐homocysteine/Choline Metabolic Network Advanced Science · 2026
    22. 766 H3K9me3 methyltransferase SETDB1 controls retrotransposon silencing, DNA methylation, constitutive heterochromatin maintenance and 3D-chromatin structure in epidermal keratinocytes 2023
    23. 1440 DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control keratinocyte differentiation and hair growth 2023
    24. Deciphering a Message from the Nucleus: How Transcription Factors and Spatial Chromatin Interactions Orchestrate Epidermal Differentiation 2023
    25. Decision letter: Live imaging reveals chromatin compaction transitions and dynamic transcriptional bursting during stem cell differentiation in vivo 2022
    26. Integrated single-cell chromatin and transcriptomic analyses of human scalp reveal etiological insights into genetic risk for hair and skin disease bioRxiv (Cold Spring Harbor Laboratory) · 2022
    27. 723 DNA dioxygenases Tet2/3 regulate gene promoter accessibility and three-dimensional chromatin topology in lineage-specific loci to control hair growth 2022
    28. 972 The ATP-dependent chromatin remodeler BRG1 controls epidermal keratinocytes migration during human cutaneous wound healing Journal of Investigative Dermatology · 2019
    29. The Role of ATP-dependent Chromatin Remodeling in the Control of Epidermal Differentiation and Skin Stem Cell Activity Stem cell biology and regenerative medicine · 2018
    30. 252 Follicle dermal papilla cells undergo chromatin remodelling processes in vivo and in vitro Journal of Investigative Dermatology · 2017