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Valproic acid helps delay hair loss and increases survival time for high-grade glioma patients undergoing radiation therapy.

Valproic Acid helps regrow hair in mice and activates a hair growth marker in human cells.

Valproate can cause hair loss and changes in hair appearance, but may help regrow hair when applied topically.

Epigenetic factors play a crucial role in skin health and disease.

A specific DNA region is crucial for Foxn1 gene expression in thymus cells but not in hair follicles.

Epigenetic mechanisms control skin development by regulating gene expression.

The nucleus is key in controlling skin growth and repair by coordinating signals, gene regulators, and epigenetic changes.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

Brg1 is crucial for keeping hair follicle stem cells and repairing skin, working with the Sonic Hedgehog pathway to promote hair growth.

ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.

Changes to the Foxp3 protein affect how well regulatory T cells can control the immune system, which could help treat immune diseases and cancer.

Malondialdehyde-modified DNA may trigger an immune response in alopecia areata patients.

SETDB1 is essential for controlling DNA methylation, silencing retrotransposons, and maintaining skin cell health, with its absence leading to skin inflammation and hair loss.

Lymphoid-specific helicase (Lsh) is crucial for skin growth, change, and healing after injury.

Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.

ASH2L is essential for skin and hair development.

Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.

The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.

Key genes can rewire networks, changing skin appendage types.

Skin stem cells remember past inflammation, helping them respond better to future injuries and possibly aiding in treating skin issues.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Understanding how EDC genes are regulated can help develop better drugs for skin diseases.

Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.

Researchers identified specific genes that are important for mouse skin cell development and healing.

Certain transcription factors are key in controlling skin stem cell behavior and could impact future treatments for skin repair and hair loss.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

BAF200 is essential for proper heart and coronary artery formation.

Epigenetic changes are crucial for stem cell behavior in skin wound healing and their disruption may lead to cancer.

The document emphasizes the importance of ongoing research and ethical considerations in genome editing and cellular reprogramming.