January 2026 in “Molecular Nutrition & Food Research” This study found that Gynostemma pentaphyllum hydrodistillate and Damulin B exert significant anti-photoaging effects in UVB-irradiated models by reducing oxidative stress, improving ECM integrity, and enhancing skin hydration and elasticity.
13 citations
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March 2019 in “Journal of ethnopharmacology” This study found that Cacumen Platycladi volatile oil promotes dermal papilla cell proliferation and enhances hair growth in mice, outperforming minoxidil and showing no obvious cytotoxic effects.
14 citations
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January 2015 in “Clinical Nutrition Research” This clinical trial found that the extract complex of Cistanche tubulosa and Laminaria japonica (MK-R7) significantly improved hair density and diameter in patients with patterned hair loss over 16 weeks.
3 citations
,
July 2020 in “Frontiers in Cell and Developmental Biology” This study found that the purified compound VB1 from Vitex negundo seeds may reduce UVA-induced skin aging by targeting MAPK1 and demonstrated its potential in mice.
1 citations
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August 2024 in “Pharmaceuticals” This study found that goat placenta extract, when combined with PEGylated liposomes and microspicule gel, significantly promoted hair regrowth in patients experiencing hair loss due to chemotherapy by enhancing hair cell proliferation without causing skin irritation over a 12-week application period.
February 2024 in “Archiv EuroMedica” This review suggests that annurca apple extract, rich in polyphenols, may be a promising alternative for treating baldness, though further research is needed to clearly assess its effectiveness compared to existing treatments.
January 2020 in “Asian journal of applied science and technology” This source provides an overview of the dietary recommendations for macronutrient intake and the benefits of plant-based diets, including meeting essential amino acid needs through combining plant proteins and the advantages of consuming complex carbohydrates and adequate fiber for health.
December 2023 in “JSFK (Jurnal Sains Farmasi Klinis)/JSFK (Jurnal Sains Farmasi dan Klinis)” This study found that a hair tonic formulated with 0.3% cocoa bean extract demonstrated the best physical stability and effectively promoted hair growth in mice, with results comparable to a positive control when used twice daily for two weeks.
20 citations
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January 2013 in “Evidence-based complementary and alternative medicine” This study found that TGPC plus CGT was more effective than CGT alone in reducing alopecia areata severity in children over 12 months, with similar safety profiles.
49 citations
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October 2017 in “Nutrients” This study observed that the ethyl acetate extract of Equisetum debile showed high activity against 5α-reductase and lipid peroxidation with no cytotoxicity on dermal papilla cells.
9 citations
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September 2018 in “Clinical, Cosmetic and Investigational Dermatology” This study found that, in female patients with idiopathic telogen effluvium, a supplement containing zinc, biotin, and other nutrients significantly improved hair loss and quality over 180 days, whereas another supplement with different ingredients had less consistent effects.
34 citations
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October 2021 in “Scientific Reports” This study found that nobiletin-loaded vesicles effectively restored skin condition in a mouse model of skin cancer, suggesting they are a promising treatment delivery system.
January 2024 in “Pharmacophore” This source discusses the potential of integrating herbal extracts with nanotechnology in skincare products, highlighting improved effectiveness and targeted delivery of active ingredients to skin cells compared to traditional formulations.
37 citations
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January 2002 in “British journal of dermatology/British journal of dermatology, Supplement” This study found that procyanidin B-2 may promote hair growth by reducing expression and inhibiting translocation of PKC isozymes in murine hair epithelial cells.
1 citations
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May 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” In laboratory studies on mice, Abstract UT-018, a stem cell chemoattractant formulation, was reported to significantly enhance wound healing and promote hair regeneration through mechanisms involving improved tissue formation, collagen organization, and follicular development.
12 citations
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March 2019 in “Cosmetics” In this study, a combined regimen of an oral supplement with Pinus pinaster, Grape seed extract, vitamins, and minerals, plus high SPF sunscreen, significantly improved mild-to-moderate facial melasma in 30 women over 84 days, reducing pigmentation and enhancing cosmetic appearance with no reported adverse effects.
This study investigated the mechanisms of Platycladi Cacumen in treating androgenetic alopecia, identifying potential key components and targets but found no specific targets or regulatory mechanisms.
25 citations
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September 2020 in “Molecules” In this study, quercitrin was reported to promote hair growth and cell viability in cultured human dermal papilla cells by enhancing cellular energy metabolism and growth factor production via MAPK/CREB signaling.
32 citations
,
December 2000 in “Phytomedicine” In this study, 1% procyanidin B-2 tonic significantly increased the number of total and terminal hairs on the scalp of male participants compared to a placebo after 6 months of use.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, the researchers introduced the Keyora Lycopene 23 in 1 formulation, demonstrating its potential to improve male endocrine and reproductive health by addressing oxidative stress, nitric oxide deficiency, androgen imbalance, and mitochondrial dysfunction through a comprehensive multi-nutrient approach.
25 citations
,
January 2019 in “Journal of Pharmacy And Bioallied Sciences” This study concluded that the formulated polyherbal shampoo is a chemical-free product with nourishing, conditioning, cleansing, and antimicrobial effects.
January 2007 in “Inpharma Weekly” Dutasteride is more effective for male pattern baldness than finasteride, and black cohosh extract BNO 1055 is as effective as conjugated estrogens in treating postmenopausal symptoms, with added benefits in reducing sweating and mental symptoms.
December 2024 in “Revista Brasileira de Plantas Medicinais” This study reviewed in vivo studies and clinical trials on phenolic compounds, like tannins and flavonoids, for treating hair loss, noting their antioxidant and anti-inflammatory effects but highlighting the need for more clinical trials to confirm benefits.
108 citations
,
October 2004 in “Anesthesiology” This review discusses surgical factors that may increase the risk of developing complex regional pain syndrome and describes potential preventive techniques but presents no new clinical results.
49 citations
,
June 2009 in “Seminars in Cutaneous Medicine and Surgery” This article examines differences in aging among ethnic populations and highlights cosmetic procedures specific to skin of color, but reports no new research findings.
19 citations
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September 2011 in “Seminars in Cutaneous Medicine and Surgery” This review discusses home-use laser and light skin devices for various dermatological purposes and reports no new clinical findings; the authors highlight the need for dermatologists to evaluate these devices' clinical value.
17 citations
,
August 2010 in “Journal of the American Academy of Dermatology” This article discusses the surgical technique of "deroofing" for hidradenitis suppurativa, highlighting its advantages over traditional methods but reports no new clinical results; the authors emphasize the importance of dietary management as part of treatment.
12 citations
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June 2019 in “Clinics in dermatology” This review highlights the use of platelet-rich plasma in dermatology for skin and hair treatments but reports no new clinical results, emphasizing the need for larger studies to validate its effectiveness.
6 citations
,
April 2025 in “Plastic and Aesthetic Research” This review highlights that biomaterial properties can be designed to modulate macrophage activity, potentially reducing foreign body responses and enhancing tissue healing in regenerative medicine.
3 citations
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February 2000 in “Dermatologic Surgery” The document concludes that hair restoration has improved with follicular unit transplantation, making it more scientific and precise.