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Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Vitamin D is important for skin health and can help treat psoriasis, atopic dermatitis, and vitiligo.

Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.

Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.

Staphylococcus epidermidis A/C strains are more antibiotic-resistant and infection-adapted, while B strains thrive in hair follicles.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Thymol-loaded nanoparticles are a promising, natural treatment for acne that avoids antibiotics and preserves healthy skin bacteria.

Alternating treatment with two drugs could help cells in a rapid aging disease.

The conclusion is that understanding how hair follicle stem cells live or die is important for maintaining healthy tissue and repairing injuries, and could help treat hair loss, but there are still challenges to overcome.

Human skin can provide stem cells for tissue repair and regeneration, but there are challenges in obtaining and growing these cells safely.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

ICAM-1 helps regulate hair growth cycles and skin remodeling.

Auto-antibody testing is a useful but not definitive tool in diagnosing interstitial lung diseases, and using a specific algorithm could make testing more cost-effective.

Boreal caribou in northeastern British Columbia have significant health issues, including infections, tick infestations, and mineral deficiencies.

Metformin may help treat neuroendocrine tumors.

Citrullinated proteins from Porphyromonas gingivalis may contribute to rheumatoid arthritis.

Testosterone can help premenopausal and postmenopausal women with low sexual desire, but its long-term safety is unclear and it's not widely approved for this use.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.

New treatments like nanotechnology show promise in improving skin cancer therapy.

TLR4 is important in aging-related diseases and could be a new treatment target.

Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.

Zinc pyrithione needs targeted delivery to the scalp for effective dandruff treatment.

All five human steroid 5α-reductase enzymes are found in the endoplasmic reticulum.

Type 1 diabetes often occurs with other autoimmune diseases, and personalized treatment based on genetics can improve outcomes.

Targeting a protein that blocks hair growth with microRNAs could lead to new hair loss treatments, but more research is needed.

Hormone levels in hair change during pregnancy, with progesterone increasing significantly compared to non-pregnant women.

Bmpr2 and Acvr2a receptors are crucial for hair retention and color.

Adding a second method to PROTACs could improve cancer treatment.

Tiny particles called extracellular vesicles show promise for treating skin conditions and promoting hair growth.