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A woman with severe angioedema improved significantly after treatment with rituximab.

Fat-derived stem cells can help protect and repair skin stem cells from aging caused by UV light.

Certain MC4R gene variants are linked to higher BMI in obese women with PCOS but do not cause PCOS.

Some patients with severe alopecia areata developed skin darkening from their treatment, which may indicate a less effective response to the therapy.

A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.

Human hair protein modifications could potentially indicate heart disease risk.

miR-133a-3p and miR-145-5p help goat hair follicle stem cells differentiate by controlling NANOG and SOX9.

Lgr5 is a marker for active, long-lasting stem cells in mouse hair follicles.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Stem cell niches support, regulate, and coordinate stem cell functions.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

K_ATP channel gene mutations are linked to heart diseases, but more research is needed to understand the connection and treatment potential.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Eclipta alba extract improved learning, memory, and stress-related ulcers in rats without affecting movement or causing anxiety.