This review discusses the role of the Wnt/β-catenin pathway in hair follicle development and how natural products that activate this signaling could be used to treat hair loss, but it reports no new experimental results.
1 citations
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January 2022 in “Food & Function” This study found that fruit extracts from certain Egyptian Sabal species demonstrated significant anti-androgenic activity and potential therapeutic effects against benign prostatic hyperplasia in rat models and cell lines.
9 citations
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March 1968 in “The BMJ” In their 1957 study, Neuman and Neuman suggested that magnesium deficiency may inhibit the ion exchange process required for calcium ions to enter extracellular fluid, potentially affecting calcium mobilization.
1 citations
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July 2016 in “Dermatologic surgery” September 2018 in “Dermatologic Surgery” This abstract describes the Dermatologic Surgery journal's focus on providing comprehensive peer-reviewed content in dermatologic surgery but reports no new research findings.
April 2025 in “Frontiers in Pharmacology” This study found that targeting RARβ and RXRA with CANA, in combination with MPA, could help overcome progestin resistance by restoring BAX levels and downregulating CRABP2, suggesting a novel strategy for improving clinical efficacy in this context.
8 citations
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October 2020 in “Pharmaceutics” This study explored using a chitosan oligomer coating for topical delivery of dutasteride-loaded nanostructured lipid carriers, aiming to reduce systemic exposure and cytotoxicity.
May 2024 in “ShodhKosh Journal of Visual and Performing Arts” This study highlights the numerous health benefits of chia seeds, including their rich nutrient profile, cardiovascular protection, digestive support, and potential cognitive and athletic performance enhancements, making them a versatile and powerful functional food for modern diets.
4 citations
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September 2024 in “Frontiers in Endocrinology” This study found that serum steroid profiling, particularly 11-deoxycortisol, can effectively differentiate between ACC and ACA, while considering sex differences and functional status for other steroids is important.
2 citations
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April 2021 in “Journal of Cosmetic Dermatology” This study found that sulforaphane and its related compounds may promote hair follicle growth in mice, suggesting their potential as treatment agents for androgenic alopecia.
28 citations
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January 2016 in “Current Pharmaceutical Biotechnology” This review discusses the traditional uses and biological activities of Aristotelia chilensis, summarizing its phytochemical composition and various potential health benefits, but reports no original research findings and highlights the need for further studies.
April 2013 in “Cancer Research” This study found that a botanical extract increased Bcl-2 levels and improved the anagen-to-telogen hair ratio in men with androgenetic alopecia, suggesting potential for managing chemotherapy-induced alopecia.
August 2024 in “Archives of Dermatological Research” This study suggests that proteins CHI3L1 and CXCL5, secreted by recovery-state dermal papilla cells, may promote hair growth by stimulating the proliferation of outer root sheath cells.
26 citations
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October 1997 in “Planta Medica” This study found that bisbenzylisoquinoline alkaloids from Stephania cepharantha Hayata stimulated growth in cultured murine hair cells but not in keratinocytes or fibroblasts.
24 citations
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April 2007 in “European Journal of Pharmaceutics and Biopharmaceutics” This study found that artocarpin delivered via alginate/chitosan microparticles effectively suppressed the growth of hamster flank organs compared to artocarpin in solution form, without significant systemic effects.
3 citations
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February 2023 in “Journal of Investigative Dermatology” Ch55 may help reduce skin scarring and fibrosis.
18 citations
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January 2002 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” This study found that several new pregnane derivatives, especially steroids 16 and 19, demonstrated higher antiandrogenic activity on male hamster models than the commonly used finasteride.
20 citations
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June 2019 in “Archives of dermatological research” In this study, combination therapy with DPCP and anthralin promoted hair regrowth in 40.62% of alopecia areata patients who were unresponsive to DPCP alone, with response improving over longer treatment durations.
3 citations
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September 2022 in “Molecules” This study found that Camellia seed cake extract may counteract DHT-induced effects in cultured dermal papilla cells, suggesting potential to prevent or alleviate androgenetic alopecia.
17 citations
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August 2014 in “The Anatomical Record” The researchers reported that scaffoldin, a protein identified in chicken embryos, likely plays a role in forming periderm granules and contributes to the soft cornification of embryonic epidermis.
December 2024 in “Applied Functional Materials” This study reported that a scalp serum containing Zanthoxylum ailanthoides extract effectively reduced inflammation and increased melanin production in cell assays, while demonstrating stable formulation and microbial safety, suggesting its potential to address scalp issues and enhance scalp health.
November 2025 in “Biomedicines” This review highlights hypochlorous acid's potential benefits in various medical fields due to its antimicrobial and healing properties but stresses the need for further research on dosing and product development.
October 2021 in “European Journal of Dermatology” In this study, the researchers reported that calcipotriol pre-treatment made photodynamic therapy more effective and safe than conventional treatment for actinic keratosis on the scalp, improving long-term clearance rates, especially for Grade II lesions. However, they suggested larger trials are necessary to corroborate these findings.
85 citations
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January 1996 in “International Journal of Cancer” In this study, AS101 combined with chemotherapy significantly reduced the severity of chemotherapy-induced alopecia in non-small-cell-lung-cancer patients and may involve immune mechanisms related to IL-1 and PGE2.
January 2023 in “Biocell” The study found that safflower extract may help protect human follicle dermal papilla cells from cisplatin-induced damage, suggesting its potential as an adjuvant in chemotherapy to mitigate hair follicle cell damage.
2 citations
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July 2025 in “Discover Chemistry.” This study explored the optimization of phytochemicals from Alstonia boonei to develop potential 5-alpha reductase inhibitors for Benign Prostatic Hyperplasia, finding promising analogs with enhanced binding affinity and stability compared to Finasteride, warranting further experimental validation.
7 citations
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May 1977 in “Deutsche medizinische Wochenschrift/Deutsche Medizinische Wochenschrift” This article discusses the mechanisms and therapeutic use of antiandrogens, specifically cyproterone acetate and chlormadinone acetate, in gynecological treatments without reporting new clinical results.
February 2025 in “Cureus” This case report describes a 37-year-old female with non-classical congenital adrenal hyperplasia who presented with severe acne, progressive hair loss, and primary infertility, managed with prednisolone.
7 citations
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January 2017 in “International Journal of Trichology” This case report describes a unique occurrence of plica polonica in a lung adenocarcinoma patient on chemotherapy, linked to anagen effluvium from paclitaxel and carboplatin and uncustomary shampoo use.
April 2011 in “HAL (Le Centre pour la Communication Scientifique Directe)” This study suggests that polymersomes decorated with chitosan improve the transdermal delivery of finasteride, providing an alternative drug delivery system with higher drug retention in the skin.