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Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

New gel formulas without ethanol and propylene glycol, containing a minoxidil-methyl-β-cyclodextrin complex, have been created for treating hair loss.

Minoxidil works well as a high permeability reference drug for biopharmaceutics classification.

Tamsulosin for enlarged prostate may increase the risk of severe low blood pressure, especially when starting or restarting the medication.

Finasteride daily doesn't affect sperm production or semen in young men.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Finasteride, a hair loss drug, has unaddressed sexual side effects due to the manufacturer's inadequate safety measures and lack of additional studies.

New method measures finasteride in plasma, finds two formulations bioequivalent.

The document concludes that doctors should carefully consider off-label drug use in dermatology and always inform patients, while more research is needed on the safety and effectiveness of such practices.

Drug advertising has greatly increased, changing consumer behavior and raising concerns about its influence on healthcare and patient protection.

Minoxidil's absorption is too variable for it to be a reliable reference drug.

A standard protocol for alopecia areata clinical trials was created to improve consistency and encourage more research.

Different drug doses approved in Japan and the U.S. are not mainly due to different clinical responses, and ethnic factors should be considered in setting drug doses.

Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.

The U.S. FDA regulates cosmetics for appearance purposes, but not as strictly as some other countries.

The CLASI is a reliable tool for measuring the severity of cutaneous lupus erythematosus.

Gendered social factors, not just biology, contribute to sex differences in adverse drug events.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

The trial showed that a new under-the-tongue treatment for severe hair loss was somewhat effective in a small group of people.

People with moderate hair loss from Alopecia Areata feel more impacted than those with no or almost complete hair loss, and are more likely to seek treatment.

Exposure to the hair loss drug finasteride during pregnancy can cause genital anomalies in male babies, but not in female babies. It's best to avoid this drug in women who could potentially become pregnant.

A method was developed to test the breakdown of Finasteride capsules, showing it can tell the difference between different brands and highlighting the need for standard tests and ingredient consistency.

The project created a standardized system for classifying skin lesions in lab rats and mice.

Finasteride effectively stops hair loss in most patients, but concerns about rare sexual side effects exist.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.

Method accurately measures finasteride concentration in medicine.

Finasteride negatively affects fish reproduction and gonadal development.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.