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Minoxidil works well as a high permeability reference drug for biopharmaceutics classification.

New gel formulas without ethanol and propylene glycol, containing a minoxidil-methyl-β-cyclodextrin complex, have been created for treating hair loss.

Drug advertising has greatly increased, changing consumer behavior and raising concerns about its influence on healthcare and patient protection.

The trial showed that a new under-the-tongue treatment for severe hair loss was somewhat effective in a small group of people.

The document concludes that doctors should carefully consider off-label drug use in dermatology and always inform patients, while more research is needed on the safety and effectiveness of such practices.

Different drug doses approved in Japan and the U.S. are not mainly due to different clinical responses, and ethnic factors should be considered in setting drug doses.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Finasteride treats enlarged prostate and baldness, but may cause limited urinary improvement and sex-related side effects.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Minoxidil's absorption is too variable for it to be a reliable reference drug.

Gendered social factors, not just biology, contribute to sex differences in adverse drug events.

Finasteride effectively stops hair loss in most patients, but concerns about rare sexual side effects exist.

Some common medications can harm male fertility, but many effects can be reversed.

The document concludes that various medications and treatments can have significant, sometimes adverse, effects on health outcomes.

Finasteride may cause suicidal thoughts and mental side effects, especially in young people with hair loss.

Finasteride, a hair loss drug, has unaddressed sexual side effects due to the manufacturer's inadequate safety measures and lack of additional studies.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Tamsulosin for enlarged prostate may increase the risk of severe low blood pressure, especially when starting or restarting the medication.

New method measures finasteride in plasma, finds two formulations bioequivalent.

Blocking Wnt/β-catenin signaling with EGF receptor is necessary for proper hair growth.

A standard protocol for alopecia areata clinical trials was created to improve consistency and encourage more research.

The CLASI is a reliable tool for measuring the severity of cutaneous lupus erythematosus.

Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.

Finasteride negatively affects fish reproduction and gonadal development.

Method accurately measures finasteride concentration in medicine.

A method was developed to test the breakdown of Finasteride capsules, showing it can tell the difference between different brands and highlighting the need for standard tests and ingredient consistency.

Method accurately measures finasteride in tablets using finasteride-BSA interaction.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

5α-reductase inhibitors may prevent prostate cancer but could also raise the risk of more severe cancers.