The Relationship Between Patient-Reported Severity of Hair Loss and Health-Related Quality of Life and Treatment Patterns Among Patients with Alopecia Areata

March 2022 in “ Dermatology and Therapy ”

Heather L. Gelhorn, Katelyn Cutts, Emily Edson-Heredia, Peter E. Wright, Amy M. DeLozier, Jerry Shapiro, Maryanne M. Senna, Antonella Tosti

Alopecia Areata autoimmune disease hair loss health-related quality of life HRQL scalp hair healthcare provider treatments for AA AA quality of life hair loss treatments

TLDR People with moderate hair loss from Alopecia Areata feel more impacted than those with no or almost complete hair loss, and are more likely to seek treatment.

The study surveyed 1327 participants with Alopecia Areata (AA), an autoimmune disease causing hair loss. It found a non-linear relationship between health-related quality of life (HRQL) and AA severity. Participants with 1-20% to 50-94% of current scalp hair missing reported higher symptom, functioning, and emotional impacts due to AA than those with 0% missing scalp hair and/or 95-100% missing scalp hair. Interestingly, participants reporting 95-100% of scalp hair missing were less likely to be currently seeing a healthcare provider and to be on treatments for AA. The study concluded that the severity of AA significantly influences the burden of illness and healthcare patterns of people living with AA.

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