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The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Different cell types work together to repair skin, and targeting them may improve healing and reduce scarring.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.

Dietary lipids affect inflammation and are crucial for normal cell function and immune health.

Skin fat has important roles in hair growth, skin repair, immune defense, and aging, and could be targeted for skin and hair treatments.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Finasteride affects frog testes by increasing testosterone, decreasing 5α-DHT, and impacting genes related to reproduction and other functions.

Skin problems in the elderly are unique and may indicate other diseases, involving changes in skin, hair, nails, and increased cancer risk.

UV radiation can help sterilize wounds and promote healing but requires careful use to avoid damaging cells.

Biomaterials combined with stem cells show promise for improving tissue repair and medical treatments.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Mesenchymal stem cells could help treat aging-related diseases better than current methods.

Zinc helps reduce the severity of depression.

Exosomes show promise for treating skin diseases and improving skin regeneration.

Exosomes could be a promising way to help repair skin and treat skin disorders.

People need different amounts of biotin based on age and it's important for health, with many foods providing enough.

Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.

Aging skin is affected by inflammation, reduced stem cell function, and slower wound healing.

Metformin, usually used for diabetes, can also help treat hair loss from alopecia areata due to its ability to reduce inflammation and stimulate new hair growth.

Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.

Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.

Epidermal keratinocytes start wound healing and inflammation after schistosome infection.

Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.

Fish oil increased cell growth and macrophages in the skin but didn't affect COX-2 expression.