The Immune System Response in COVID-19 Infection in Polycystic Ovary Syndrome

    May 2021 in “ International Journal Of Medical Science And Clinical Invention ”
    Gülcan Arusoğlu, Kübra Bozay
    Image of study
    TLDR Women with PCOS may have a higher risk of severe COVID-19 due to hormonal imbalances and vitamin D deficiency.
    The document discusses the potential increased risk of severe COVID-19 infection in women with Polycystic Ovary Syndrome (PCOS), a condition affecting 8-13% of women of reproductive age. The study suggests that women with PCOS, due to hyperandrogenism, may have a 51% higher risk of COVID-19 compared to women without PCOS. The renin-angiotensin system (RAS) shows higher activation in hyperandrogenic women with PCOS, potentially leading to a hyperinflammatory condition that could increase susceptibility to infection. Additionally, 67-85% of women with PCOS have a vitamin D deficiency, which could impair the immune response and increase the risk of systemic infections, including COVID-19. The document recommends that clinicians evaluate the COVID-19 risk profile of women with PCOS and provide practical recommendations for treatment changes and self-isolation.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 19 results

      community How does hair loss and recovery work?

      in Chat  12 upvotes 1 year ago
      Hair loss varies due to genetic sensitivity to DHT and other factors. Treatments discussed include finasteride, minoxidil, RU58841, and microneedling.

      community Sugar and Hair loss connections

      in Research/Science  41 upvotes 4 months ago
      High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

      community C’est terrible - at my wits end

      in Female  450 upvotes 1 year ago
      A 29-year-old woman is experiencing gradual hair thinning since age 15, suspects Androgenic Alopecia, and has tried 5% minoxidil with little success. She has purchased various hair loss treatments including minoxidil, dutasteride, finasteride, and spironolactone, but is cautious about starting them due to potential interactions with her ADHD medication.

      community PCOS Hair Loss: What’s Helped Me (and What Didn’t)

      in Treatment  9 upvotes 3 weeks ago
      OP shares their experience with PCOS-related hair loss, highlighting that addressing vitamin D and ferritin deficiencies, managing hormones with spironolactone, and using gentle hair care products helped improve their condition. They advise against relying on "miracle" hair oils and emphasize the importance of medical evaluation and a combined approach to treatment.

    Related Research

    4 / 4 results