2 citations
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September 2022 in “Cellular and molecular biology” In this study, Agaricus bisporus derived β-Glucan particles demonstrated antimicrobial, antioxidant, and anticancer effects against cervical cancer HeLa cells, suggesting potential as a therapeutic option.
February 2024 in “Advanced Science” This study highlights that a novel radially aligned nanofiber scaffold with dual growth factor gradients significantly enhances wound healing, promoting cell migration, epidermal regeneration, and angiogenesis, ultimately leading to improved wound closure, immune regulation, and tissue remodeling compared to other groups.
April 2023 in “Authorea (Authorea)” This case report describes the presentation of a 32-year-old Iranian immunocompetent female diagnosed with Merkel Cell Carcinoma, highlighting the importance of early diagnosis and management to mitigate complications.
This study found that estradiol affects hair growth in mice by regulating the transition of hair follicles from rest to growth phases via the estrogen receptor pathway in the dermal papilla.
14 citations
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July 2016 in “Anatomical Science International” This study revealed that in androgenic alopecia, the proximal attachment of the arrector pili muscle to the hair follicle is often lost or significantly reduced.
2 citations
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September 2017 in “Journal of Zoo and Wildlife Medicine” This case report presents the first known instance of cutaneous lymphoma in a nondomestic bovid, documented in a 13-year-old addax.
March 2026 in “Dermatopathology” In this case report, a rare instance of a primary cutaneous granular cell tumor with prominent overlying terminal hair growth in an adult is described, highlighting the importance of recognizing atypical presentations to accurately diagnose similar uncommon neoplasms.
July 2025 in “Journal of Investigative Dermatology” Three molecular subtypes of advanced skin T-cell lymphoma were identified, with potential biomarkers for predicting treatment response and disease progression.
2 citations
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February 2012 in “PubMed” This study found that Gp₄G increased hair length, papilla cell numbers, and versican deposition in treated animals, potentially through alterations in hair follicle phases and nucleotide concentrations.
July 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers observed that TCDD exposure in mice enhanced sebaceous gland differentiation and lipid production before causing seboatrophy, providing insights into the cellular events that may contribute to chloracne pathogenesis.
In this study, researchers observed a high degree of plasticity in somatosensory axons innervating Merkel cells in adult mouse skin, with both epithelial and neural components exhibiting dynamic remodeling, highlighting intricate epithelial-neural interactions in maintaining homeostasis.
130 citations
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August 2015 in “Experimental Dermatology” This review provides a comprehensive guide to serum-free human hair follicle organ culture methods, highlighting research opportunities, standardization efforts, and potential applications without reporting new empirical findings.
10 citations
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December 2018 in “Medical Science Monitor” This study suggests that the MAPK/ERK signaling pathway plays a role in the regulation of cell proliferation, apoptosis, and cycling in rat urethral plate fibroblasts affected by finasteride-induced hypospadias.
7 citations
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January 2016 in “Laboratory Investigation” TR3 is mainly found in hair follicle stem cells and may be involved in hair loss.
April 2023 in “Dermatology practical & conceptual” This study concluded that lenalidomide significantly induces the proliferation and migration of melanocyte stem cells, enhancing their differentiation into functional melanocytes in a mouse model.
January 2017 in “DR-NTU (Nanyang Technological University)” This study observed that keratin sponges showed comparable biocompatibility to a commercial positive control in mice, but keratin gels had slightly inferior biocompatibility.
32 citations
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March 2014 in “PLOS ONE” This study demonstrates that FMOD deficiency in mice alters TGF-β ligand and receptor expression during wound healing stages, leading to delayed wound closure and increased scar size.
238 citations
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March 2013 in “Development” This study found that adipocytes play a crucial role in skin wound healing by facilitating fibroblast recruitment and dermal reconstruction during the healing process.
90 citations
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June 2006 in “The American Journal of Dermatopathology” This review outlines the classification, histopathologic presentation, and pathogenetic concepts of scarring and nonscarring alopecias, reporting no new clinical results and emphasizing the need for clinicopathologic correlation.
27 citations
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February 2003 in “Cell and Tissue Research” This study found that FM dyes are effective markers for tracing live Merkel cells in in vitro experiments, as they remain visible for at least seven days and highlight cell shape better than quinacrine.
8 citations
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July 2015 in “European journal of histochemistry” This study found that Sox9 was variably expressed in most canine skin neoplasms, particularly in those originating from the hair follicle's bulge region, suggesting its potential as a stem cell marker.
7 citations
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August 2017 in “PloS one” This study found that NIH hairless mice exhibit abnormalities in hair growth and immune-related pathways, with Pik3r1 and Pik3r3 identified as key genes for further investigation.
7 citations
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May 2010 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This preliminary study observed that melanoblasts are preserved in the white hair follicles of segmental vitiligo lesions.
1 citations
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May 2023 in “PubMed” The researchers in this study identified a new subpopulation of dermal fibroblasts in neonatal murine dermis marked by EGFR, which they report contributes to hair follicle regeneration through the promotion of IGF1, potentially aiding in wound-induced hair follicle neogenesis.
November 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that hemoglobin α expression in the epidermis is induced by oxidative stress and may function as an antioxidant, contributing to skin barrier function.
42 citations
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December 1990 in “The Journal of Dermatologic Surgery and Oncology” This study found decreased hair density and altered follicular architecture in the balding frontal scalp of patients with androgenic alopecia, with increased vellus hairs noted.
26 citations
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July 2007 in “Biochemical Pharmacology” This study found that phenyl-imidazole sulfonamide derivatives, particularly ISCK03, inhibited c-kit signaling and promoted depigmentation in various experimental settings, suggesting potential use as skin-whitening agents.
2 citations
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January 2003 in “PubMed” This study found that in individuals with androgenetic alopecia, the expression of apoptosis-related markers differed significantly between affected and unaffected scalp areas.
April 2018 in “Journal of Investigative Dermatology” This study found that claudins CLDN1 and CLDN3 are crucial for maintaining proper hair follicle structure in mice, and their dysregulation may lead to telogen hair loss.
This study found that putative hair follicle stem cells can successfully be cultured from the bulge area of hair follicles for up to four days, suggesting potential for further development of culture techniques.