Histological Evaluation of Hair Keratin Based Templates in Mice

    January 2017 in “ DR-NTU (Nanyang Technological University) ”
    Brennan Kiah Hui Lee
    TLDR Keratin sponges are as biocompatible as collagen, but keratin gels are slightly less so.
    The study evaluated human hair keratin-based templates in mice using histological techniques to assess their biocompatibility for potential biomedical applications. Two types of keratin templates, gel and sponge, were compared to a commercial collagen control. Hematoxylin and eosin staining and immunoperoxidase staining were used to analyze tissue integration, vascularization, cell penetration, degradation, inflammation, and ECM formation. Results indicated that keratin gels had slightly inferior biocompatibility compared to the control, while keratin sponges showed comparable biocompatibility. Although the findings were not conclusive, they suggested that keratin has potential in biomedical applications, warranting further research.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Let's talk keratin products and hair loss

      in Styling  2 upvotes 2 months ago
      OP is considering using a keratin gel to improve hair quality and is concerned about its safety and visual impact on a slightly balding crown. Users discuss shampoo frequency, with some suggesting less frequent use for better hair health, but OP prefers regular shampoo and conditioner for silky hair.

      community Keratin microspheres - breakthrough

      in Research/Science  15 upvotes 1 year ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community Losing ground after 14 months of fin use and 11 months of min

      in Finasteride/Dutasteride  52 upvotes 3 years ago
      A 24-year-old person who is worried about their hair loss after 14 months of taking finasteride and 11 months of minoxidil. Replies to the post suggested sticking with their current regimen, that shedding from one part may not be telogen effluvium, and that shedding is normal with these drugs and they should evaluate in two to three months.

      community New & Improved Hair Growth Stack for Maximum Results

      in Treatment  5 upvotes 10 months ago
      A user shared a hair growth stack using minoxidil sulfate, valproic acid, bimatoprost, blue copper peptide, and other ingredients, emphasizing a gel-based formula for better skin tolerance. Another user suggested adding a 5-alpha-reductase inhibitor like finasteride or dutasteride for more effective long-term results.

      community Growth Stimulants that aren't Minoxidil...?

      in Research/Science  7 upvotes 1 year ago
      The user is exploring hair growth stimulants other than Minoxidil, mentioning Stemoxydine, various peptides, drugs like Latanoprost and Bimatoprost, and natural remedies such as Rosemary Oil and Caffeine. They express concerns about the long-term effectiveness and safety of these alternatives and seek more information on viable options for hair regrowth.

    Similar Research

    6 / 1000+ results