January 2017 in “DR-NTU (Nanyang Technological University)” This study observed that keratin sponges showed comparable biocompatibility to a commercial positive control in mice, but keratin gels had slightly inferior biocompatibility.
53 citations
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September 2004 in “American journal of medical genetics. Part C, Seminars in medical genetics” This review discusses the range of diseases caused by mutations in keratin intermediate filament genes and presents no new clinical findings; the authors note the diverse phenotypes within this molecular category.
48 citations
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March 2020 in “Stem Cell Research & Therapy” This study found that human adipose-derived stem cells co-cultured on a collagen sponge scaffold showed increased differentiation into keratinocytes, suggesting potential for improved skin wound healing.
1 citations
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January 2016 in “Frontiers in Bioengineering and Biotechnology” This study reports that keratin-based materials derived from human hair have potential for use in tissue engineering, showing promising bioactivity and mechanical support in preliminary evaluations.
14 citations
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January 2015 in “Skin Appendage Disorders” This study examined severe skin reactions, including erythema and eczema-like lesions, associated with Brazilian keratin treatment, suggesting a drug reaction phenomenon rather than solely irritant or allergic origin.