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This study observed that keratin sponges showed comparable biocompatibility to a commercial positive control in mice, but keratin gels had slightly inferior biocompatibility.

This review discusses the range of diseases caused by mutations in keratin intermediate filament genes and presents no new clinical findings; the authors note the diverse phenotypes within this molecular category.

This study found that human adipose-derived stem cells co-cultured on a collagen sponge scaffold showed increased differentiation into keratinocytes, suggesting potential for improved skin wound healing.

This study reports that keratin-based materials derived from human hair have potential for use in tissue engineering, showing promising bioactivity and mechanical support in preliminary evaluations.

This study examined severe skin reactions, including erythema and eczema-like lesions, associated with Brazilian keratin treatment, suggesting a drug reaction phenomenon rather than solely irritant or allergic origin.

This study demonstrated the potential of epithelial cell scaffolds fabricated with various materials for effective hair regeneration, highlighting their promising application in tissue engineering for alopecia treatment.

In this study, a porous keratin hydrogel derived from wool hair demonstrated strong mechanical properties and supported the growth of various animal cells, indicating potential as a scaffold in tissue engineering.

This study demonstrated that keratin derived from human hair can improve axon extension and alleviate motor deficits from sciatic nerve injuries, highlighting its potential as a promising biomaterial for peripheral nerve regeneration.

This study found that scaffolds made from human hair proteins supported better cell growth and interactions than control surfaces, indicating potential use in tissue engineering.

This study demonstrated the potential of newly fabricated epithelial cell scaffolds to enhance hair regeneration, showing promise for future alopecia treatments.

This study reports promising preliminary results for using monoclonal antibodies to identify cashmere fibers, highlighting observed immunological differences from wool keratins.

This review discusses the potential risks of formaldehyde in hair keratin treatments like Brazilian blow-dry, and reports no new clinical results; it emphasizes the need for greater safety assessments including occupational exposure.

This study proposes a new method to selectively isolate keratin-associated proteins and keratin from human hair, suggesting that KAPs may support keratin fibers in hair structure.

This study observed that hepatocyte adhesion to human hair keratin biomaterials was mediated by the hepatic ASGPR, as blocking this receptor reduced cell attachment.

This article reviews the complex structure and molecular composition of hair keratins, highlighting their self-assembly process and implications for keratin extraction techniques, but reports no new experimental results.

This Ph.D. project aims to evaluate the self-assembling potential of hair keratin extracts and study the cellular response to both crude and purified keratins, highlighting their potential applications from biomedical to water remediation.

This research found that keratin hydrogels derived from human hair may support cell viability and proliferation, indicating potential as 2D and 3D soft tissue culture scaffolds.

In this study, researchers demonstrated that human hair keratins can self-assemble into stable nanofibrous networks in vitro, which are compatible with human skin cells and useful for regenerative applications.

This review summarizes the cell type distribution and functional significance of human keratins, emphasizing their roles in tumor diagnosis and potential clinical applications, and reports no new clinical findings.

Keratins are crucial for cell structure, growth, and disease risk.

This review discusses keratin disorders and potential RNA interference therapeutics, reporting no new clinical findings but highlighting the promise of siRNA for future treatments.

In this study, expressing human K16 in the epidermis of K14 null mice prevented early skin blistering but led to age-related anomalies, indicating K16 and K14 have distinct roles despite their sequence similarity.

This study suggests that adjusting the ratios of keratin-associated proteins to keratin intermediate filaments can create keratin/chitosan hydrogels with more consistent gel properties for tissue engineering.

This study explored a keratin, sodium alginate, and carboxymethyl chitosan hydrogel modified with tannic acid and found it to have promising wound-healing qualities, including similar elasticity to human skin, antimicrobial and antioxidant properties, and effective water retention. These attributes suggest potential applications in biomedical engineering.

This study found that serine 44 in the N-terminal head domain of keratin 17 is phosphorylated in response to various stimuli affecting skin keratinocyte growth, linking K17 up-regulation with growth and stress responses in skin epithelium.

This article reviews the role of keratins in epithelial function and structure, discussing their involvement in growth control, organelle functions, and pathomechanisms of disorders, but reports no new clinical results.

In this study, a keratin hydrogel improved survival rates and functional recovery in rats with spinal cord injuries, suggesting potential for SCI treatment that merits further investigation.

This study found that beard hair medulla cells express an unexpected range of keratins, showing variability and promiscuous behavior in keratin interactions distinct from other hair follicle cells.

This study demonstrates that keratin K2 is crucial for proper keratinocyte structure and function in specific mouse skin areas, and its deficiency leads to cellular aggregates and skin abnormalities.

This study reported that transgenic mice with targeted TNF alpha expression in keratinocytes showed impaired weight gain, retarded hair growth, and skin changes, leading to cachexia and necrosis.