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ODC overexpression in hair cells increases tumor growth by reducing Notch signaling.

The research suggests new treatments for skin cancer could target specific cell growth pathways.

The lentiviral array can monitor and predict gene activity during stem cell differentiation.

Targeting TGFβ can improve skin immunity in older people.

A virus protein can activate a pathway that may lead to abnormal hair follicle development.

Reviewers suggest clarifying the abstract, adding background on inflammation's effect on cancer, discussing immune cell roles, including counter studies, and correcting grammar.

The reviewers found the manuscript on inflammation's role in cancer stem cells to be relevant but suggested it needs clarity, more background information, discussion on immune cells' role in tumors, updated references, and grammar corrections.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

Linoleic acid from Malva verticillata seeds may help treat hair loss by promoting hair cell growth and blocking baldness signals.

Foxp1 helps control hair stem cell growth and response to stress during hair growth cycles.

The document concludes that a protein involved in hair growth may link to baldness and that more research is needed on its role in hair loss and skin cancer treatments.

The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.

The conclusion is that grasping how cells determine their roles through evolution is key, with expected progress from new research models and genome editing.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.

Blocking Wnt signaling in young mice causes thymus shrinkage and cell loss, but recovery is possible when the block is removed.

Skin cysts might help advance stem cell treatments to repair skin.

Fat tissue and a specific protein are crucial for healthy hair growth and maintenance.

Wnt signaling is important for development and cell regulation but can cause diseases like cancer when not working properly.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

Wnt10b helps blood stem cells grow after injury.

The enzymes Tet2 and Tet3 are important for skin cell development and hair growth.

PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.

The conclusion is that accurately replicating the complexity of the extracellular matrix in the lab is crucial for creating realistic human tissue models.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Hair follicle cells help maintain and support stem cells and blood cell formation.

The revised manuscript on how inflammation affects cancer stem cells was accepted after addressing issues with clarity and detail.

The revised study on how inflammation affects cancer stem cells was accepted after improving clarity and structure.

Pro-IGF-II improves muscle repair in old mice.

β-Catenin signaling is involved in brain cell growth after injury and could be a therapy target.