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    Glossary Cell Junctions

    specialized structures connecting adjacent cells within tissues

    Cell junctions, also known as intercellular junctions, are specialized structures that connect adjacent cells within tissues. They play crucial roles in maintaining the structural integrity of tissues, facilitating communication between cells, and regulating the passage of substances. Examples include tight junctions, which create a seal to prevent leakage; desmosomes, which provide mechanical strength; and gap junctions, which allow for the direct transfer of ions and small molecules between cells.

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    1. Wnt4 increases the thickness of the epidermis in burn wounds by activating canonical Wnt signalling and decreasing the cell junctions between epidermal cells Burns & Trauma · 2022 · 1 citations
    2. Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions PLOS ONE · 2011 · 61 citations
    3. Patched1 Functions as a Gatekeeper by Promoting Cell Cycle Progression Cancer Research · 2006 · 176 citations
    4. The role of cell–cell and cell–matrix junctional complexes in sebaceous gland homeostasis and differentiation Cell Communication and Signaling · 2024 · 6 citations
    5. 277 HPV8 E6 induced STAT3 activation leads to hair follicle junctional zone keratinocyte stem cell proliferation and expansion in actinic keratoses 2023
    6. Cell Type-specific Functions of the Lysosomal Protease Cathepsin L in the Heart Journal of Biological Chemistry · 2007 · 56 citations
    7. 1391 Cell death functions in hair follicle regeneration Journal of Investigative Dermatology · 2023
    8. Fibroblast heterogeneity and functions: insights from single-cell sequencing in wound healing, breast cancer, ovarian cancer and melanoma Frontiers in genetics · 2024
    9. Recent advances on skin‐resident stem/progenitor cell functions in skin regeneration, aging and cancers and novel anti‐aging and cancer therapies Journal of Cellular and Molecular Medicine · 2009 · 36 citations
    10. ISID1391 – Cell death functions in hair follicle regeneration 2023
    11. 22 Biological functions of exosome-like nanoparticles isolated from rose (rosa damascena) stem cell culture (RSCE) 2023
    12. Planar cell polarity-dependent and independent functions in the emergence of tissue-scale hair follicle patterns Developmental Biology · 2017 · 33 citations
    13. Skin γδ T cell subsets have distinct functions in alopecia areata 3844 The Journal of Immunology · 2025
    14. Regulation of adult stem cell quiescence and its functions in the maintenance of tissue integrity Nature Reviews Molecular Cell Biology · 2023 · 200 citations
    15. 877 Integration of magnetic tweezers and traction force microscopy for exploring the mechanobiology of keratinocyte cell-cell and cell-matrix anchoring junctions Journal of Investigative Dermatology · 2018
    16. Hair, Cutaneous Homeostasis and Stem Cell Functions Journal of Investigative Dermatology · 2014
    17. Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion PloS one · 2012 · 72 citations
    18. Distinctive T Cell Patterns Defining Lymphocytic Alopecia and Alternate Autoimmune and Stem Cell Pathways, Linked to Pleiotropic Functions of Regulatory T Cells Within iSALT American Journal of Dermatopathology · 2026
    19. Genome-wide analysis of Musashi-2 targets reveals novel functions in governing epithelial cell migration Nucleic Acids Research · 2016 · 66 citations
    20. Interleukin-25-Mediated-IL-17RB Upregulation Promotes Cutaneous Wound Healing in Diabetic Mice by Improving Endothelial Cell Functions Frontiers in Immunology · 2022 · 34 citations
    21. N1-methylspermidine, a stable spermidine analog, prolongs anagen and regulates epithelial stem cell functions in human hair follicles Archives of dermatological research · 2015 · 13 citations
    22. Establishment of keratinocyte cell lines from human hair follicles Scientific reports · 2018 · 16 citations
    23. Targeting the stem cell niche: role of collagen XVII in skin aging and wound repair Theranostics · 2022 · 9 citations
    24. Transcriptome Profiling of Pilosebaceous Units in Male Androgenetic Alopecia Reveals Altered Junctional Networks Journal of Investigative Dermatology · 2021
    25. Intercellular junctions in normal epidermis Experimental Dermatology · 2004 · 2 citations
    26. Facial pore refining by targeting dermal and epidermal functions: Assessment across age and gender Journal of Cosmetic Dermatology · 2024 · 6 citations
    27. Oestrogen functions in skin and skin appendages Expert Opinion on Therapeutic Targets · 2005 · 68 citations
    28. The functions of ocu-miR-205 in regulating hair follicle development in Rex rabbits BMC Developmental Biology · 2020 · 32 citations
    29. Metabolic Teamwork in the Stem Cell Niche Cell metabolism · 2017 · 14 citations
    30. Cell Surface B2m-Free Human Leukocyte Antigen (HLA) Monomers and Dimers: Are They Neo-HLA Class and Proto-HLA? Biomolecules · 2023 · 3 citations