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Notch signaling disruptions can cause various skin diseases.

Dermatological drugs and cosmetics can cause serious side effects like cancer, allergies, and heart issues.

Keratin from hair and wool is used in medical materials for healing and drug delivery.

TGM3 is important for skin and hair structure and may help diagnose cancer.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

Plet-1 protein helps hair follicle cells move and stick to tissues.

New synthetic polymers help improve skin wound healing and can be enhanced by adding natural materials and medicines.

Skin stem cells in hair follicles are important for touch sensation.

Cactus extract from Notocactus ottonis may help promote hair growth.

Conductive hydrogels show promise for medical uses like healing wounds and tissue regeneration but need improvements in safety and stability.

The composite sponge helps heal diabetic wounds by reducing inflammation and promoting new blood vessel growth.

RPGRIP1L helps skin cells stick together by blocking PKCβII, which can prevent skin blistering like in pemphigus.

The niche environment controls stem cell behavior and plasticity, which is important for tissue health and repair.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Temporary ROS production in cultured human hair follicles promotes growth and stem cell activation.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Tcf3 helps cells move and heal wounds by controlling lipocalin 2.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

Fetal cells could improve skin repair with minimal scarring and are a potential ready-to-use solution for tissue engineering.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

SCF and ET-1 together significantly increase skin pigmentation and melanin production.

The hydrogels help harvest cells while preserving their mechanical memory, which could improve wound healing.

Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.

Ionizing radiation causes irreversible skin damage, with single doses leading to acute injury and hair graying, and fractional doses causing more severe long-term tissue damage.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Researchers found four key stages of cell development that are important for hair growth and shedding in cashmere goats.

Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Compartmentalized organization might be crucial for stem cells to effectively respond to growth or injury.