research Macrophage Activation Syndrome in a Patient with Systemic Lupus Erythematosus
A patient with lupus experienced a condition where their immune cells became overactive.
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research Time-Course RNA-Seq Analysis Reveals Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Hair Follicle Growth Cycle in Goats
Melatonin affects different genes and pathways important for goat hair growth.
research Normolipemic Xanthoma Associated With Folliculotropic Mycosis Fungoides
A man with a type of skin lymphoma had unusual yellowish skin growths despite normal blood lipid levels, and treatment reduced some symptoms but not the growths.
research Present and Future Use of Exosomes in Dermatology
Exosomes could be key in treating skin conditions and healing wounds.
research Recurrent Pseudolymphomatous Reaction to Ear Piercing: 20-Year History
A woman had a rare reaction to ear piercing that caused earlobe swelling, which was best treated by removing the piercing and not re-piercing.
research Development and Characterization of Polydeoxyribonucleotide Loaded Chitosan Polyplex for Wound Healing
The chitosan/PDRN polyplex improved wound healing in diabetic rats.
research Extracellular Vesicles Released by Hair Follicle and Adipose Mesenchymal Stromal Cells Induce Comparable Neuroprotective and Anti-Inflammatory Effects in Primary Neuronal and Microglial Cultures
Hair follicle and adipose cell vesicles both protect neurons and reduce inflammation similarly.
research Targeting Pathogenic MICA-NKG2D Interactions by Statins: A Novel Adjunct Treatment Strategy for Alopecia Areata Management?
Statins may help treat alopecia areata by reducing harmful immune interactions.
research Mite Burden and Immunophenotypic Response to Demodex Musculi in Swiss Webster, BALB/c, C57BL/6, and NSG Mice
NSG mice had the most mites, and genetic factors affect immune response and susceptibility.
research Mechanosensitive Lymphocytes Potentiate Wound Repair by Regulating Inflammation and Extracellular Matrix
Lymphocytes, a type of immune cell, are crucial for wound healing as they help remodel damaged areas and reduce inflammation.
research Intestinal Intraepithelial Lymphocytes: Sentinels of the Mucosal Barrier
Intestinal intraepithelial lymphocytes are crucial for gut immunity and maintaining the mucosal barrier.
research Autoimmunity: Alopecia Areata
Alopecia areata is an autoimmune disease causing hair loss, treatable with immune-modulating drugs, and linked to genetics.
research Immunology of the Human Nail Apparatus: The Nail Matrix Is a Site of Relative Immune Privilege
The nail matrix has a reduced immune response, protecting it from autoimmunity.
research Efficacy of Topical Sensitizers in the Treatment of Alopecia Areata
Topical sensitizers have mixed success in treating alopecia areata.
research Role of Cytotoxic T Cells in Chronic Alopecia Areata
Cytotoxic T cells cause hair loss in chronic alopecia areata.
research The Pathobiology of Skin Aging
Skin aging is a complex process influenced by various factors, leading to wrinkles and sagging, and should be considered a disease due to its health impacts.
research A Subset of TREM2+ Dermal Macrophages Secretes Oncostatin M to Maintain Hair Follicle Stem Cell Quiescence and Inhibit Hair Growth
Certain immune cells in the skin release a protein that stops hair growth by keeping hair stem cells inactive.
research Natural Killer Cells in Atopic and Autoimmune Skin Diseases
NK cells play a role in skin diseases like eczema and psoriasis.
research Hair Regrowth in Alopecia Areata Patients Following Stem Cell Educator Therapy
Stem Cell Educator therapy helps regrow hair and improve life quality in alopecia areata patients.
research Targeting Integrin Pathways: Mechanisms and Advances in Therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research Macrophage-Derived Extracellular Vesicle Promotes Hair Growth
Special cell particles from macrophages can help hair grow.
research Loss of Epidermal Evi/Wls Results in a Phenotype Resembling Psoriasiform Dermatitis
Loss of a specific protein in skin cells causes symptoms similar to psoriasis.
research Altered Dermal Fibroblasts in Systemic Sclerosis Display Podoplanin and CD90
Fibroblast changes in systemic sclerosis may help understand disease severity and treatment.
research Mice Engrafted with Human Fetal Thymic Tissue and Hematopoietic Stem Cells Develop Pathology Resembling Chronic Graft-Versus-Host Disease
Mice with human fetal thymic tissue and stem cells developed symptoms similar to chronic graft-versus-host disease.
research Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata
MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
research Selective Inhibition of JAK3 Signaling Is Sufficient to Reverse Alopecia Areata
Blocking JAK3 signaling can reverse hair loss from alopecia areata.
research RANKL Induces Organized Lymph Node Growth by Stromal Cell Proliferation
RANKL causes lymph nodes to grow by making certain cells multiply.
research Sustained Exosome-Guided Macrophage Polarization Using Hydrolytically Degradable PEG Hydrogels for Cutaneous Wound Healing: Identification of Key Proteins and miRNAs, and Sustained Release Formulation
Hydrogel with M2-derived exosomes improves wound healing by slowly releasing exosomes that help reduce inflammation and promote tissue repair.
research Malt1 Protease Is Critical in Maintaining Function of Regulatory T Cells and May Be a Therapeutic Target for Antitumor Immunity
Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.
research Extracellular Vesicles from Activated Dermal Fibroblasts Stimulate Hair Follicle Growth Through Dermal Papilla-Secreted Norrin
Special particles from skin cells can promote hair growth by activating a specific growth signal.