November 2023 in “Frontiers in cell and developmental biology” Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.
170 citations
,
January 2013 in “Journal of Investigative Dermatology” Wnt ligands are crucial for hair growth and repair.
79 citations
,
January 2015 in “Journal of Materials Chemistry B” Smart biomaterials that guide tissue repair are key for future medical treatments.
13 citations
,
September 2020 in “International Journal of Molecular Sciences” PRP therapy and minoxidil combo works best for male hair loss.
6 citations
,
August 2019 in “Experimental Dermatology” Skin can produce blood cells, often due to disease, which might lead to new treatments for skin and blood conditions.
1 citations
,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
53 citations
,
May 2014 in “Experimental Dermatology” Wnt10b makes hair follicles bigger, but DKK1 can reverse this effect.
10 citations
,
November 2021 in “Biomedicines” Some therapies using stem cells and platelet-rich plasma may help treat osteoarthritis, but more research is needed to ensure they are safe and effective.
10 citations
,
October 2020 in “Frontiers in Cell and Developmental Biology” Wounds can regenerate hair in young mice, but this ability declines with age, offering insights for improving tissue regeneration in the elderly.
1 citations
,
December 2023 in “iScience” A protein called desmoglein 3 is important for keeping hair follicle stem cells inactive and helps in their regeneration.
1 citations
,
December 2023 in “Life” PRP helps skin heal, possibly through special cells called telocytes.
9 citations
,
June 2021 in “Nutrients” Fisetin in fruits and vegetables helps hair growth in mice.
225 citations
,
April 2018 in “Journal of Investigative Dermatology” Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.
39 citations
,
March 2015 in “International journal for parasitology/International Journal for Parasitology” Epidermal keratinocytes start wound healing and inflammation after schistosome infection.
14 citations
,
February 2020 in “Scientific reports” Telocytes in the scalp may help with skin regeneration and maintenance.
13 citations
,
January 2018 in “Stem cells” Low-dose radiation affects hair stem cell function and survival by changing their genetic material's structure.
1 citations
,
January 2016 in “Journal of stem cell research and medicine” Fat-derived stem cell therapies can potentially increase hair growth and thickness in people with hair loss.
1 citations
,
January 2016 in “Journal of stem cell research and medicine” Fat-derived stem cell therapies can potentially increase hair growth and thickness in people with hair loss.
February 2024 in “International Journal of Molecular Sciences” Hair loss in Androgenetic Alopecia is caused by genetics, aging, and lifestyle, leading to hair follicle shrinkage and related health risks.
8 citations
,
September 2013 in “Molecular carcinogenesis” Rapamycin reduces skin cell growth and tumor development by affecting cell signaling in mice.
1 citations
,
June 2023 in “Journal of Cosmetic Dermatology” Exosome treatment for hair growth is promising but not FDA-approved and needs more research on safety and how it works.
5 citations
,
March 2022 in “Stem cell reports” Thymic stromal lymphopoietin (TSLP) promotes hair growth, especially after skin injury.
36 citations
,
October 2015 in “Cell reports” Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.
November 2023 in “Journal of allergy and clinical Immunology. Global” A 10-month-old boy with a rare combination of genetic conditions has severe immune deficiency and treatment challenges.
6 citations
,
January 2015 in “Journal of regenerative medicine & tissue engineering” The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.
20 citations
,
February 2020 in “Stem Cells” Hes1 protein is important for hair growth and regeneration, and could be a potential treatment for hair loss.
January 2018 in “Stem cells in clinical applications” Exosomes show promise for tissue repair and regeneration with advantages over traditional cell therapies.
May 2014 in “Transfusion and Apheresis Science” PRP is a safe natural treatment that improves skin by reducing wrinkles and enhancing texture for up to 4 months.
May 2014 in “Transfusion and Apheresis Science” PRP treatment showed no hair regrowth improvement after the first application in patients with alopecia.
57 citations
,
January 2017 in “Journal of Dermatological Treatment” PRP therapy may effectively treat hair loss, but more research needed.