Adipose-Derived Stem Cell-Based Therapies for Male/Female Pattern Hair Loss

The document from 7 years ago discussed the potential of adipose-derived stem cells (ASCs) in treating Alopecia Androgenetica, a condition causing hair loss in about 50% of males and 45% of females in the U.S. The condition leads to finer hair growth and reduced hair density due to a decrease in the anagen phase of the hair cycle. The document highlighted studies conducted between 2010 and 2015, which showed that therapies based on ASCs, such as cell-assisted lipotransfer (CAL) or adipose-derived stem cell conditioned media (ADSC-CM), significantly enhanced cell proliferation and hair growth. For instance, a 2015 study involving 27 women reported a 16.4% increase in hair density and an 11.3% increase in hair thickness after a 12-week treatment course with ADSC-CM. These therapies showed reduced side effects compared to other treatments and were effective in both males and females. However, the need for larger, controlled clinical trials to establish the safety and efficacy of these therapies was emphasized.