Hair Growth Stimulated by Allogenic Adipose-Derived Stem Cells Supplemented with ATP in a Mouse Model of Dihydrotestosterone-Induced Androgenetic Alopecia

    June 2025 in “ Stem Cell Research & Therapy ”
    Eduardo López Bran, L Perez, Patricia Esteban, María Luisa González-Morales
    Studysummary This study found that administering adipose-derived stem cells with ATP improved hair regrowth in male mice with androgenetic alopecia, while the combination was less effective in female mice.
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    Research cited in this study 10

    1. Androgenetic Alopecia: Therapy Update Drugs · 2023
    2. Hair Shaft Miniaturization Causes Stem Cell Depletion Through Mechanosensory Signals Mediated by a Piezo1-Calcium-TNF-α Axis Cell Stem Cell · 2021
    3. A Randomized, Double-Blind, Vehicle-Controlled Clinical Study of Hair Regeneration Using Adipose-Derived Stem Cell Constituent Extract in Androgenetic Alopecia Stem Cells Translational Medicine · 2020
    4. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019
    5. Therapeutic Potential of Stem Cells in Follicle Regeneration Stem Cells International · 2018
    6. A Systematic Review of Topical Finasteride in the Treatment of Androgenetic Alopecia in Men and Women PubMed · 2018
    7. Autologous Adipose-Derived Stem Cell Versus Platelet-Rich Plasma Injection in the Treatment of Androgenetic Alopecia: Efficacy, Side Effects, and Safety Journal of clinical & experimental dermatology research · 2018
    8. Stem Cells from Human Hair Follicles: First Mechanical Isolation for Immediate Autologous Clinical Use in Androgenetic Alopecia and Hair Loss Stem cell investigation · 2017
    9. Stem Cell Therapy as a Novel Therapeutic Intervention for Resistant Cases of Alopecia Areata and Androgenetic Alopecia Journal of Dermatological Treatment · 2016
    10. Different Levels of 5α-Reductase Type I and II, Aromatase, and Androgen Receptor in Hair Follicles of Women and Men with Androgenetic Alopecia Journal of Investigative Dermatology · 1997

    Related research 3

    1. Progenic Hair Regrowth Treatment: The Use of Platelet-Released Growth Factors for Treating Androgenetic Alopecia by Activating Hair Follicle Stem Cells Journal of clinical & experimental dermatology research · 2014
    2. Fullerene Nanomaterials Potentiate Hair Growth Nanomedicine · 2009
    3. Towards a Molecular Understanding of Hair Loss and Its Treatment Trends in Molecular Medicine · 2001