August 2019 in “Research Square (Research Square)” This study explored how long non-coding RNA mediates the effects of FGF5 on the hair follicle development and villus growth of Liaoning cashmere goats.
5 citations
,
December 1996 in “Biochemical and Biophysical Research Communications” In this study, keratin genes mHa1 and mHb4 were unable to form an extensive keratin network in one cell line, altering endogenous keratin distribution, but showed better integration in another cell line.
158 citations
,
November 1998 in “Cell” β-catenin affects hair growth and can lead to tumors, needing more research for better understanding.
3 citations
,
May 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, researchers found that skin pigmentation alterations in a mouse model of Carney complex may be caused by specific dermal fibroblasts promoting melanogenic signaling.
February 2016 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” This study reports a novel mutation in the TP63 gene associated with T and B cell lymphopenia in an EEC patient, suggesting that EEC diagnosis should include TREC assay and evaluation for immunodeficiency.
1 citations
,
April 2019 in “Journal of Investigative Dermatology” This case study describes successful hair growth in a 59-year-old African-American female with central centrifugal cicatricial alopecia after switching to oral minoxidil treatment.
14 citations
,
April 2019 in “Genes” This study identified a genetic locus associated with coat type in domestic dogs, showing certain variants linked to single-coated breeds and suggesting potential regulatory roles.
3 citations
,
June 2004 in “Critical Care Nurse” This article reviews the importance of genomics in critical care nursing and highlights the need for nurses to understand genetic concepts and advancements to improve patient care, without providing new results.
This study found that the rs3185480 polymorphism in the APCDD1 gene was associated with an elevated risk of developing androgenic alopecia and reduced protein levels, potentially due to altered codon usage affecting translation efficiency.
1 citations
,
April 2017 in “Journal of Investigative Dermatology” This study suggests that alkaline phosphatase-regulated expression of CCL5 contributes to the trichogenicity of human dermal papilla spheres.
September 2024 in “The Journal of Dermatology” In this study, researchers reported a rare case of nevus comedonicus with hair growth in a 26-year-old male, challenging prior reports that affected lesions typically lack the capability to develop terminal hair.
February 2026 in “International Journal of Molecular Sciences” In this study, the researchers found that cholinergic signaling via M4 muscarinic receptors influences hair growth, with enhanced elongation observed upon activation with bethanechol, highlighting its potential role in hair biology using mouse models.
2 citations
,
November 2022 in “Acta crystallographica. Section B, Structural science, crystal engineering and materials./Acta crystallographica. Section B, Structural science, crystal engineering and materials” This study reports the synthesis and structural characterization of a novel dinuclear platinum(III) complex with potential antitumor and catalytic activity.
July 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers found that the efflux of calcium in root hairs of Arabidopsis thaliana, particularly through the ER-localized ACA2 and ACA7, is crucial for modulating cytoplasmic calcium signals and enabling proper root hair growth, with disruptions leading to impaired elongation.
30 citations
,
January 2021 in “Journal of Clinical Immunology” This study describes various clinical phenotypes associated with FOXN1 mutations, finding that affected individuals may develop different severities of immunodeficiency based on their genetic mutations.
8 citations
,
May 2017 in “IUBMB life” This review discusses the role of astrotactins in development and their genetic mutations' links to a variety of human diseases, but reports no new clinical results.
245 citations
,
January 1998 in “Genes & Development” This study found that Hoxc13 mutations in mice cause defects in hair, nail, and tongue structures, with the most noticeable issue being brittle hair leading to alopecia.
2 citations
,
December 2019 in “Al-ʻulūm al-ṣaydalāniyyaẗ” This study found no evidence that CTLA-4 gene polymorphism (rs733618) plays a role in polycystic ovarian syndrome among the participants.
12 citations
,
April 2022 in “Frontiers in Cell and Developmental Biology” This study found that stabilizing β-catenin in a specific mouse model led to temporarily increased hair density but ultimately accelerated hair follicle aging and hair thinning.
January 1964 in “OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)” This study found that platelet-secreted chemokines like CXCL7 are crucial for early neutrophil recruitment and efficient muscle regeneration in injured mice.
44 citations
,
September 2016 in “American Journal Of Pathology” This study identified a subpopulation of neural crest-derived progenitor cells in human corneal endothelial tissue from normal and Fuchs endothelial corneal dystrophy donors, which may have potential for future cell therapy development.
January 2024 in “Bratislavské lekárske listy/Bratislava medical journal” This study examined the vasorelaxant effects of two similar alkaloids, chloroquine and cinchonine, in a model of smooth muscle contractions induced by phenylephrine. Results are not reported in the abstract.
2 citations
,
January 2024 in “Proceedings of the National Academy of Sciences of the United States of America” This study developed a multiscale spatial atlas of healthy skin and basal cell carcinoma, revealing a hair follicle origin for BCC and the expansion of specific cell populations such as POSTN+ fibroblasts and RGS5+ pericytes, suggesting roles in skin cancer stroma expansion and vascular remodeling.
1 citations
,
July 2016 in “Livestock science” This study suggests that nerve growth factor may support hair follicle growth in Liaoning cashmere goats through pathways involving its receptor, TrkA, particularly during the anagen phase.
This research found that nod factor can induce root hair reorientation and gene expression in Medicago truncatula with as little as a single molecule, implicating heterotrimeric G-protein signaling in this process.
July 2026 in “Theranostics” This study developed a novel ferritin-based delivery system (LR@Fn) that effectively co-delivers RG108 and LLY283 for hearing loss treatment in animal models, reducing hair cell loss and synaptic damage more effectively than dexamethasone.
7 citations
,
March 2022 in “The FASEB journal” This study observed that mice with a whole-body deficiency of Cystathionine-β-synthase developed severe hyperhomocysteinemia and related mild symptoms without increased mortality, indicating HHCy may not directly cause end organ damage.
99 citations
,
August 1998 in “Pain” This study found that blocking GABA(A) receptors in cat dorsal horn neurons increased evoked activity and background discharge, highlighting differences in inhibitory control systems compared to glycine receptors.
January 2026 in “International Journal of Molecular Sciences” In this study, researchers identified S100a4 as a critical regulator of secondary hair follicle stem cells in cashmere goats, linking its expression to follicle regeneration and differentiation pathways, which may have implications for enhancing cashmere fiber production.
4 citations
,
April 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study presents an improved reference genome for the African spiny mouse, which may aid in understanding its tissue regeneration at the molecular level.