Treatment of Central Centrifugal Cicatricial Alopecia with Oral Minoxidil

April 2019 in “ Journal of Investigative Dermatology ”

A. Alame, T. Vandergriff, K.O. Ayoade

central centrifugal cicatricial alopecia CCCA primary cicatricial alopecia scarring hair loss carboplatin docetaxel doxycycline topical minoxidil minoxidil foam 5% oral minoxidil Rogaine

TLDR Oral minoxidil can potentially increase hair growth in people suffering from Central Centrifugal Cicatricial Alopecia.

In 2019, a case study was conducted on a 59-year-old African-American female suffering from Central Centrifugal Cicatricial Alopecia (CCCA), a subtype of primary cicatricial alopecia that primarily affects persons of African descent and results in progressive scarring hair loss. The patient had a history of invasive ductal carcinoma of the right breast and was treated with a carboplatin and docetaxel chemotherapy regimen. She presented with hair loss and a scalp biopsy revealed a marked decrease in hair follicles and prominent fibrous tracts consistent with CCCA. Initial treatments with doxycycline to reduce inflammation and topical minoxidil foam 5% showed no improvement in hair growth. However, when topical minoxidil was switched to oral minoxidil, the patient demonstrated increased hair growth on the scalp over time. This case suggests that oral minoxidil could be an effective treatment option for CCCA.

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community Finasteride doesn't work for me in 2 years and my bloodtest result just came in.

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community lost my hair in a single year of treatment at 20 years old

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A 20-year-old lost significant hair after one year of treatment, using minoxidil, finasteride, and later dutasteride. They are considering adding RU58841 but are advised to return to finasteride and minoxidil for a year before deciding.

community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 2 years ago

In this conversation, 4990 discussed various treatments for hair loss, including oral minoxidil, PRP, transplan, Jak inhibitors, Dutasteride, Finasteride, Olumiant, Ketoconazole, RU58841, microneedling, baricitinib, and CCCA. They recommended scalp biopsies in unclear cases of DUPA, twice weekly to twice daily shampooing for topical minoxidil users, and two sessions spaced one month apart with follow up at month three to determine the effectiveness of PRP treatment.

community Wanted to say that Derma rolling and Pumpkin seed oil helped my crown out.

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community Exploring Bryan Johnson's Hair Routine In Detail

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