Treatment of Central Centrifugal Cicatricial Alopecia with Oral Minoxidil

April 2019 in “ Journal of Investigative Dermatology ”

A. Alame, T. Vandergriff, K.O. Ayoade

central centrifugal cicatricial alopecia CCCA primary cicatricial alopecia scarring hair loss carboplatin docetaxel doxycycline topical minoxidil minoxidil foam 5% oral minoxidil Rogaine

TLDR Oral minoxidil can potentially increase hair growth in people suffering from Central Centrifugal Cicatricial Alopecia.

In 2019, a case study was conducted on a 59-year-old African-American female suffering from Central Centrifugal Cicatricial Alopecia (CCCA), a subtype of primary cicatricial alopecia that primarily affects persons of African descent and results in progressive scarring hair loss. The patient had a history of invasive ductal carcinoma of the right breast and was treated with a carboplatin and docetaxel chemotherapy regimen. She presented with hair loss and a scalp biopsy revealed a marked decrease in hair follicles and prominent fibrous tracts consistent with CCCA. Initial treatments with doxycycline to reduce inflammation and topical minoxidil foam 5% showed no improvement in hair growth. However, when topical minoxidil was switched to oral minoxidil, the patient demonstrated increased hair growth on the scalp over time. This case suggests that oral minoxidil could be an effective treatment option for CCCA.

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community lost my hair in a single year of treatment at 20 years old

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community I am a dermatologist with a clinical interest in alopecia. AMA

in Will treatment work for me? 2 years ago

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community Wanted to say that Derma rolling and Pumpkin seed oil helped my crown out.

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