Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review explores the expression of Perforin by gamma delta T cells in human skin and its role in cytotoxicity but reports no new experimental results.

This study used single-cell RNA sequencing to create a detailed atlas of human scalp hair follicles and found that early-stage hair graying involves matrix hair progenitor depletion linked to P53 pathway activation.

This study found that the expression of laminin-511 and -332 was significantly increased in psoriasis skin lesions and may influence keratinocyte proliferation and apoptosis, suggesting a previously overlooked role in the disease's pathogenesis.

This study found that diphencyprone showed a significant clinical response for treating alopecia areata, while tacrolimus was not effective.

In this study, researchers using the hair paradigm highlighted how periodic patterning and compartmentalization enable diverse regenerative behaviors, including region-specific renewal cycles and emergent properties like regenerative waves in organ populations.

This study found that immune cells, including T cells and macrophages, significantly influence stem cell behavior and tissue regeneration by secreting cytokines and inflammatory factors in mice.

This study found that metabolism-related genes significantly impact the prognosis and metastasis in breast cancer, and the development of prediction models may guide personalized therapeutic strategies.

This study found that mixtures used in permanent hair dyes had irritant effects on reconstructed human epidermis, while individual ingredients alone did not.

This study reports that immunologically inert and skewed immune cell populations in developing human skin may contribute to wound healing and structural changes during skin development.

In this study, basal cell carcinoma developed in Ptch-deficient mice only after chemical treatment, not skin wounding, suggesting a second unknown event is necessary for tumor formation.

In this study, topical quercetin was found to stimulate hair follicle growth and promote microvascular regrowth in mice, suggesting its potential for hair regrowth strategies.

In this study, researchers found that non-invasive analysis of skin surface lipid RNAs revealed alterations in gene expression patterns associated with atopic dermatitis, suggesting its potential for understanding skin disease pathophysiology.

This study suggests that mammalian hair follicles may serve as a viable and non-invasive system for diagnosing traumatic brain injury, reflecting similar molecular responses observed in other tissues.

This study found that M30 may protect against cyclophosphamide-induced alopecia in mice by enhancing hair growth and preventing abnormal hair, suggesting its potential as a treatment.

This review discusses insights from scar-free animal models and cellular factors in skin regeneration, suggesting potential strategies for developing scar-free treatments in clinical and cosmetic practices, but reports no new clinical results.

This study found that carbonic anhydrase II was significantly upregulated in human keratinocytes when treated with toll-like receptor 3 agonist and Th2 cytokines, suggesting its potential role in inflammatory skin conditions.

This review examines current and potential approaches to managing chronic wound inflammation through macrophage-targeted strategies using ECM-inspired wound dressings, but it reports no new clinical results.

This review discusses the role of fibroblast heterogeneity in kidney pathology, particularly their contribution to tertiary lymphoid tissue formation, and reports no new results.

This review discusses the importance of heme oxygenase in skin physiology and disease, but it reports no new clinical results; the authors highlight its potential as a treatment target for conditions like atopic dermatitis and psoriasis.

This review discusses the development of the MATH+ treatment protocol for COVID-19 patients, detailing its scientific and clinical rationale, but reports no new experimental findings.

This study found that specific SNPs in the CXCL1 and CXCL2 genes may be associated with increased susceptibility to alopecia areata in the Korean population.

This study found that hairless mice with homozygous mutations developed significantly more aggressive basal cell carcinomas and a heightened inflammatory response to UVB exposure compared to their haired littermates.

This study observed that the topical skin-whitening agent rhododendrol induced skin depigmentation in approximately 16,000 consumers, linked to melanocyte cytotoxicity and immune reactions.

This study found that adult patients with Myotonic Dystrophy type 1 exhibited a higher prevalence of various morphofunctional, inflammatory, and proliferative skin disorders compared to healthy controls.

This article reviews the role of keratins in epithelial function and structure, discussing their involvement in growth control, organelle functions, and pathomechanisms of disorders, but reports no new clinical results.

This study found that Si Jun Zi Tang may have anti-aging effects in mice, linked to inhibition of the PI3K-AKT and P38 MAPK signaling pathways.

This review examines recent findings on COVID-19 pneumonia treatment using mesenchymal stem cells and reports no new clinical results; the authors highlight MSCs' potential due to their immunomodulatory and tissue-regenerative properties.

This review highlights that biomaterial properties can be designed to modulate macrophage activity, potentially reducing foreign body responses and enhancing tissue healing in regenerative medicine.

This study found that topically applied liposomal spherical nucleic acids targeting the IL-17 receptor could effectively reduce psoriasis severity in preclinical models.

SA linked to mitochondrial issues and oxidative stress, while AGA involves disrupted hair growth genes.