Search
for

    Glossary Castration

    surgical removal of testicles in males

    Castration, also known as neutering or orchiectomy, is the surgical removal of the testicles in males. This procedure is commonly performed on animals to prevent reproduction and reduce aggressive behavior, but it can also be done in humans for medical reasons such as hormone-related cancers.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Intratumoral <i>De Novo</i> Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors Cancer research · 2011 · 402 citations
    2. Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts The Journal of Steroid Biochemistry and Molecular Biology · 2009 · 57 citations
    3. Prevention and treatment of experimental prostate cancer in lobund-wistar rats. I. Effects of estradiol, dihydrotestosterone, and castration 1989 · 31 citations
    4. Genetic variants in AR and SHBG and resistance to hormonal castration in prostate cancer Medical Oncology · 2013 · 6 citations
    5. Exogenous testosterone, finasteride and castration effects on testosterone, insulin, zinc and chromium in adult male rats. PubMed · 2013 · 4 citations
    6. Effect of Exogenous Testosterone, Finasteride, and Castration on serum level of Thyroxin PubMed · 2013 · 1 citations
    7. Effects of Castration on BPH 2016
    8. Low-Dose Dimethyl Sulfoxide (DMSO) Suppresses Androgen Receptor (AR) and Its Splice Variant AR-V7 in Castration-Resistant Prostate Cancer (CRPC) Cells Therapeutics · 2025
    9. Impact of Medical Castration on Malignant Arrhythmias in Patients With Prostate Cancer Journal of the American Heart Association · 2021 · 8 citations
    10. Inconsistent effects of surgical and chemical castration on arterial baroreceptor dysfunction and cardiac and brainstem inflammation in endotoxic rats The FASEB Journal · 2020
    11. Insight into Recent Advances in Degrading Androgen Receptor for Castration-Resistant Prostate Cancer Cancers · 2024
    12. Gender Differences in Mouse Skin Morphology and Specific Effects of Sex Steroids and Dehydroepiandrosterone Journal of Investigative Dermatology · 2005 · 168 citations
    13. Androgen receptor–mediated inhibition of cutaneous wound healing 2002 · 108 citations
    14. Regulatory roles of androgens in cutaneous wound healing Thrombosis and Haemostasis · 2003 · 58 citations
    15. Effects of androgen deprivation on chronic bacterial prostatitis in a rat model International Journal of Urology · 2003 · 38 citations
    16. Redefining hormone resistance in prostate cancer Therapeutic Advances in Medical Oncology · 2009 · 38 citations
    17. HSD3B1 Genotypes Conferring Adrenal-Restrictive and Adrenal-Permissive Phenotypes in Prostate Cancer and Beyond Endocrinology · 2019 · 30 citations
    18. Thyroid and gonadal regulation of hair growth during the seasonal molt in the male European badger, Meles meles L General and comparative endocrinology · 1987 · 29 citations
    19. Androgen receptor in rat liver: Characterization and separation from a male-specific estrogen-binding protein Archives of biochemistry and biophysics · 1989 · 24 citations
    20. Simultaneous quantitation of nine hydroxy-androgens and their conjugates in human serum by stable isotope dilution liquid chromatography electrospray ionization tandem mass spectrometry 2017 · 22 citations
    21. Endocrinology of the Aging Prostate: Current Concepts Frontiers in Endocrinology · 2021 · 21 citations
    22. Influence of age and of testosterone on the response of male rats to parachlorophenylalanine British Journal of Pharmacology · 1972 · 18 citations
    23. Recent discoveries and developments of androgen receptor based therapy for prostate cancer MedChemComm · 2015 · 17 citations
    24. Deslorelin for the treatment of hair cycle arrest in intact male dogs Veterinary dermatology · 2014 · 10 citations
    25. Androgen receptor–mediated inhibition of cutaneous wound healing 2002 · 9 citations
    26. 해김사(海金沙)가 Rat의 전립선비대에 미치는 영향 The Journal of Internal Korean Medicine · 2010 · 5 citations
    27. Alopecia X em cães: revisão PubVet · 2020 · 4 citations
    28. Androgenic modulation of arterial baroreceptor dysfunction and neuroinflammation in endotoxic male rats Brain Research · 2021 · 2 citations
    29. Cardiac and brainstem neuroinflammatory pathways account for androgenic incitement of cardiovascular and autonomic manifestations in endotoxic male rats Journal of Cardiovascular Pharmacology · 2021 · 1 citations
    30. Cardiac and Medullary Neuroinflammatory Pathways Trigger Androgenic Incitement of Cardiovascular Sequels of Endotoxemia in Rats The FASEB Journal · 2020