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This study reported that among 10 tested 2-(4-chlorophenyl)-5-aryl-1,3,4-oxadiazole compounds, compound 4c showed the highest activity against cancer cell lines, with a 95.37% average growth rate.

A new compound that could treat various androgen-related conditions was created and analyzed.

This study found that cepharanthine may be a promising treatment for enterovirus infections, as it offered full protection to mice against lethal EV71 challenges and reduced viral titers and pathology.

This study synthesized and evaluated hydroxycinnamate derivatives for their ability to inhibit human SRD5A1, finding that three compounds showed significant inhibitory activity and low cytotoxicity. Compound 10a notably reduced SRD5A1 protein expression in cells, suggesting potential for nonsteroidal treatment of androgen-related conditions.

This study established a sensitive and reproducible method for determining the levels of four organic solvents in finasteride raw materials, meeting the requirements of the Chinese Pharmacopeia.

This study identified over 40 phytochemical compounds in the leaves and flowers of Bituminaria bituminosa, predominantly glycosylated flavonoids from apigenin, using advanced chromatographic techniques.

This study investigated the effects of cedrol on colorectal cancer and found that it inhibited cell proliferation and induced cell cycle arrest and apoptosis in cell models, while in vivo, it suppressed cancer progression and improved survival at a well-tolerated dose.

In this quasi-experimental study, researchers explored the optimal formulation of a nanoemulsion containing candlenut ethanol extract, finding that specific combinations of tween 80, span 80, and sonication time affected its physical properties and stability, although further activity testing is needed.

This study developed lipid-core nanocapsules for encapsulating menthol, improving its solubility and thermal stability, and demonstrated their safety and rapid skin absorption in ex vivo tests, highlighting potential applications for cosmeceuticals.

This research describes the synthesis of 16β-chloro- and 16β-bromo-cyproterone acetate, detailing the chemical processes involved, but reports no clinical outcomes.

The document concludes that a compound with potential for treating prostate cancer and hair loss was successfully made and its detailed structure was confirmed.

This study identified novel compounds from Bombax ceiba stem bark, including shamimicin, with potent hypotensive effects, and reported that a specific fraction had adverse effects on heart, liver, and kidneys in mice.

This review discusses the traditional uses, chemical components, and biological activities of Calanthe species, reporting no new findings; it underscores the need for conservation and further pharmacological research.

This study concluded that CNGC14 is a calcium-permeable channel crucial for polarized tip growth in Arabidopsis root hairs, but other channels may also influence the observed calcium influx.

This study demonstrated that steroidal carbamates 7–10 altered mRNA expression related to lipid metabolism in hamster flank organs and inhibited 5α-reductase activity without binding to the progesterone receptor.

This study found that treating asymptomatic or mild COVID-19 with cepharanthine did not significantly reduce the time to a negative test result, though 60 mg/day showed a non-significant trend needing further validation.

This study characterized the SARM PF-05314882, finding it demonstrates anabolic activity in rats with minimal effects on the prostate, seminal vesicles, and luteinizing hormone levels.

This study identified the structures of cyclohexyl and phenyl analog impurities in finasteride using HPLC and spectral analysis.

This study investigated the molecular mechanisms behind the formation of drug-polymer inclusion complexes and found that carbamazepine can self-assemble into stable channel structures without guest polymers, unlike griseofulvin, which requires guest molecules for structural stability.

This study found that extracts from Geranium pyrenaicum show promising antioxidant, enzyme inhibitory, and antiviral activities, particularly the methanolic extract's antiviral activity against HSV-1.

In this study, the wood essential oil of *Juniperus morrisonicola* exhibited significant anti-inflammatory activity, notably inhibiting nitric oxide production in stimulated macrophages, and showed cytotoxic effects against liver cancer cells, suggesting its potential for drug development and eco-friendly applications.

This study found that Croton membranaceus root extract induced CYP1A2 and GSTM1 enzymes but inhibited CYP3A4 and CYP2D6 in rat livers, suggesting caution in its use with other drugs.

In this study, the n-hexane fraction of Carthamus oxyacantha methanolic extract exhibited significant 5α-reductase inhibitory activity in vitro, suggesting potential therapeutic use for benign prostatic hyperplasia through DHT inhibition.

This study found that Cacumen Platycladi volatile oil promotes dermal papilla cell proliferation and enhances hair growth in mice, outperforming minoxidil and showing no obvious cytotoxic effects.

This laboratory study concluded that TRPA1 and TRPV1 channels do not play a role in mechanotransduction processes in slowly adapting type II mechanoreceptors in isolated rat sinus hair follicles.

This study found that extracts from Calotropis gigantea and Tridax procumbens individually demonstrated greater anti-inflammatory activity than Ibuprofen in a carrageenin-induced paw edema model.

This study found that CNGC 6, CNGC 9, and CNGC 14 are crucial for maintaining calcium oscillations necessary for normal root hair growth in plants, with mutations leading to defects like swelling and bursting.

In this study, cedrol was found to reduce lipid accumulation in the liver and adipose tissues of dexamethasone-treated mice by antagonizing glucocorticoid receptors, suggesting its potential utility in treating dexamethasone-induced lipid metabolism disorders.

This study found that cepharanthine significantly inhibits EqHV-8 infection in vitro and improves lung tissue pathology in infected mice by reducing oxidative stress through specific signaling pathways, suggesting its potential as a treatment for equid herpesvirus type 8.