21 citations
,
August 1987 in “Archives of Dermatology” This communication reports previously unreported side effects, severe bullous dermatosis and onycholysis, in three patients undergoing high-dose methotrexate and leucovorin calcium therapy, impacting their chemotherapy schedules.
December 2023 in “Sains Malaysiana” In this study, researchers used in silico mutagenesis to identify key calcium-binding sites influencing the stability of Rand protease from Bacillus subtilis, potentially enhancing its application in industries like leather dehairing by improving stability and eliminating the need for additional metal ions during the process.
16 citations
,
May 2015 in “Tissue Engineering Part C-methods” This study found that expanding hair follicle keratinocytes with a fibroblast feeder followed by short-term coculture with dermal papilla cells could restore their ability to form new hair follicles.
April 2019 in “Journal of Investigative Dermatology” This study reported that gain-of-function mutations in TRPV3 lead to hair loss in mice by disrupting inner root sheath keratinocyte differentiation, ultimately causing follicular keratinocyte stem cell exhaustion and permanent follicle disruption.
4 citations
,
June 2013 in “The Journal of Rheumatology” This abstract describes a program with various presentations and events focused on Canadian excellence in rheumatology but reports no new research findings.
2 citations
,
September 1978 in “Anatomia Histologia Embryologia” This study observed that alkaline phosphatase activity in dog hair follicles varied with hair cycle stages, displaying weak to negative reactions in the anagen stage, positive reactions in catagen, and strong positivity in telogen.
39 citations
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June 2023 in “Frontiers in Medicine” This review found limited but suggestive evidence that Calcium Hydroxylapatite may promote skin regeneration through increased collagen production, cell proliferation, and angiogenesis, although most studies had methodological limitations.
January 2024 in “Universidad Peruana Cayetano Heredia Institutional Repository” In this in vitro study, simple centrifugation with calcium gluconate activation led to a significantly higher release of PDGF-BB in PRP compared to other methods, which may inform improved clinical PRP preparation protocols.
September 2024 in “American Journal of Modern Physics” This study used X-ray fluorescence to analyze elemental and heavy metal contents in Senegalese powdered milk, finding potential safety concerns with excessive calcium in certain samples and significantly high potassium levels in one, suggesting ongoing monitoring is crucial for consumer safety.
March 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers developed a new method called Enriched-GF, which enhances growth factor recovery from platelet concentrates through a combination of glass bead activation, freeze-thaw cycling, and calcium stimulation, outperforming conventional methods by providing higher and more consistent yields for regenerative medicine applications.
January 2023 in “Methods in molecular biology” This article reviews methods for examining the localization and activity of ROP GTPase, cortical microtubule organization, and F-actin dynamics in plant cell models, but reports no new experimental results.
67 citations
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June 2019 in “Proceedings of the National Academy of Sciences” This study introduces a method for long-term expansion of adult mouse epidermal stem cells in vitro using an organoid culture system that maintains the basal-apical organization.
9 citations
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May 2019 in “Vestnik dermatologii i venerologii” This study demonstrated a method for delivering a photosensitizer, Ammi majus fructuum furocumarines, into hair follicles using calcium carbonate particles, followed by UVA irradiation, which led to significant pigment accumulation, indicating potential improvements for photochemical therapy.
6 citations
,
April 2018 in “Facial Plastic Surgery” This article reviews methods for temple region rejuvenation and reports no new clinical results; the authors emphasize the importance of understanding temple anatomy for optimal aesthetic outcomes.
1 citations
,
December 2010 in “Elsevier eBooks” This review covers cell transplantation methods for genitourinary reconstruction, discussing tissue sources and complications but presenting no new clinical findings.
1 citations
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October 2021 in “QJM: An International Journal of Medicine” This study found that platelet-rich plasma prepared using a double-spin method may be more effective for treating female pattern hair loss than single-spin PRP, although VEGF concentration was unaffected by either preparation method.
December 2025 in “Asian Journal of Advanced Research and Reports” This study found that measuring stress biomarkers in hair could be an effective and simpler method for assessing chronic stress in rats, potentially offering a novel alternative to serum tests with biomarkers including sodium, calcium, and cortisol.
July 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, researchers developed a novel method using ultrasound stimulation and a hydrogel delivery system to enhance the regenerative effects of stem cell-derived extracellular vesicles on severe skin injuries, resulting in improved healing and hair follicle regeneration in a mouse model.
February 2023 in “American Journal of Biomedical and Life Sciences” The researchers reported that hair bio element median derivatives bioassay is an effective and reliable method for evaluating the nutritional status of various bio elements, offering a non-invasive approach for nutritional health surveillance and precision medicine.
August 1994 in “Toxicology in Vitro” This study standardized a reproducible three-dimensional human skin model for testing skin tumor promoters, using methods that do not require human skin sourcing.
2 citations
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January 1993 This study found that human trichohyalin has a unique protein sequence potentially contributing to at least three important functions in hair follicle and epidermal cells.
January 2026 in “New Journal of Chemistry” This study synthesized calcium citrate nanoparticles to improve the solubility and reduce the irritation of minoxidil solutions for treating androgenetic alopecia.
56 citations
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March 2017 in “Plant and Cell Physiology” This study used light sheet fluorescence microscopy to successfully image and analyze calcium oscillations in the root hairs of Arabidopsis thaliana, finding that these oscillations correlate with the root hair growth rate and that auxin affects these properties.
8 citations
,
September 2014 in “Journal of X-Ray Science and Technology” This study found that hair analysis may be useful in early breast cancer detection by identifying distinct calcium and strontium concentration patterns before and during cancer development.
4 citations
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November 1981 in “Indian Journal of Dermatology Venereology and Leprology” This study observed that oral calcium pantothenate may reverse hair greying in some adolescent cases, as seen in two girls whose grey hairs turned black after treatment.
3 citations
,
April 2021 in “PLoS ONE” The authors concluded that controlling voltage, pulse width, and calcium concentration in pulse electric field-activated platelet-rich plasma enhances the release of growth factors and serotonin without causing clot formation, suggesting potential clinical advantages over bovine thrombin-activated PRP.
September 2023 in “Environmental health perspectives. Supplements” This study found that children in Alcalá may have lower exposure to calcium and strontium compared to peers in other regions, based on scalp-hair analysis.
June 2010 in “Journal of Veterinary Clinics” This study established an experimental model to visualize calcium ion distribution after skin barrier damage in canine epidermis, observing that calcium gradients changed differently depending on the type of damage and time elapsed.
January 2010 in “JOURNAL of SIBERIAN MEDICAL SCIENCES” This study found indications of phosphorus-calcium exchange abnormalities in children with chronic renal disease before kidney insufficiency, suggesting that early diagnostic methods like ultrasonic osteodensitometry could be beneficial.
Hair can show daily calcium changes, linked to body calcium levels and influenced by hormones, and can help assess calcium metabolism issues.