The best way to apply vitamin C to the skin is with a nanostructured lipid carrier formulation.
5 citations,
November 2021 in “Frontiers in Cell and Developmental Biology” Caffeine can damage hearing cells and affect hearing recovery after ear trauma.
October 2014 in “Archives of disease in childhood” Childhood cancer diagnosis leads to long-term physical and emotional health issues in parents.
8 citations,
April 2020 in “European Journal of Nutrition” Newborns' hair shows how much caffeine their mothers drank during pregnancy.
February 2025 in “Healthcare” Caffeine may help with hair loss, but more research is needed.
Caffeine in cosmetics has antioxidant effects, protects against UV, reduces cellulite, and stimulates hair growth.
2 citations,
January 2012 in “International Journal of Trichology” Coffee and tea might help hair growth in balding individuals, but side effects and alternative uses are being considered.
6 citations,
August 2021 in “International Journal of Cosmetic Science” Using antioxidants on the scalp can make it healthier and decrease hair loss.
61 citations,
May 2014 in “International journal of pharmaceutics” Nanocrystals improve skin penetration and stability of caffeine, suggesting a new method for delivering similar substances through the skin.
Nanoparticles with caffeine can be used for slow, continuous hair growth stimulation.
July 2022 in “http://isrctn.com/” Adding a cosmetic gel with caffeine, taurine, and growth factors to standard hair loss treatments could improve results.
42 citations,
July 2014 in “European journal of pharmaceutics and biopharmaceutics” Caffeine nanocrystals for skin products stay stable with the right stabilizer, but grow in size at higher temperatures.
94 citations,
May 2011 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.
82 citations,
May 2009 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.
1 citations,
March 2022 in “Protection convergence” Fermented green coffee beans may be good for scalp and hair health cosmetics.
11 citations,
January 2012 in “International Journal of Trichology” Caffeine may help hair growth in hereditary hair loss.
January 2024 in “Estetologia Medyczna i Kosmetologia” Most hair loss shampoos have unproven active ingredients.
April 2023 in “Journal of Investigative Dermatology” Cinchona succirubra extract with caffeine improves hair growth and reduces hair loss.
2 citations,
July 2021 in “Dermatologic Therapy” A woman's hair loss after COVID-19 was likely due to a mix of pressure-induced alopecia and acute telogen effluvium.
January 2022 in “DOAJ (DOAJ: Directory of Open Access Journals)” Argan oil-based nano carriers could potentially deliver caffeine to hair follicles to treat hair loss.
3 citations,
January 2023 in “International Journal of Cosmetic Science” Coffee and its by-products are promising for skin health benefits in cosmetics and help reduce environmental impact.
1 citations,
July 2021 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” Rubbing skin increases absorption of water-soluble drugs from lotions and creams, but not oil-soluble drugs.
7 citations,
July 2018 in “International Journal of Applied Pharmaceutics” Chitosan nanoparticles are promising for sustained caffeine delivery through the skin.
January 2020 in “Estetologia Medyczna i Kosmetologia” Most ingredients in anti-hair loss products lack scientific proof of effectiveness.
The optimal concentration for caffeine release in gel form is 0.2% caffeine and 2.3% chitosan.
January 2021 in “AIP conference proceedings” A hair serum made from coffee by-products can promote hair growth and is safe, but needs less stickiness.
August 2015 in “Arquivo Brasileiro de Medicina Veterinária e Zootecnia/Arquivo brasileiro de medicina veterinária e zootecnia” Caffeine intake during pregnancy and lactation can cause skin lesions in mother rats and their babies, not linked to cortisol levels.
November 2023 in “Journal of Cosmetic Dermatology” The topical treatment with caffeine and Procapil 3% improved male pattern hair loss and was well tolerated after 12 weeks.
12 citations,
March 2012 in “ATLA. Alternatives to laboratory animals” Hair follicles significantly affect the skin absorption of some drugs.
2 citations,
January 2016 Optimized formulations with specific ingredients can significantly improve skin delivery of topical drugs.