15 citations,
October 2020 in “European journal of pharmaceutics and biopharmaceutics” Caffeine penetrates skin quickly through open hair follicles, but less through closed ones, with levels becoming equal after 22 hours.
Caffeine can potentially treat common hair loss by counteracting hair follicle shrinkage caused by hormones.
94 citations,
May 2011 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.
61 citations,
May 2014 in “International journal of pharmaceutics” Nanocrystals improve skin penetration and stability of caffeine, suggesting a new method for delivering similar substances through the skin.
10 citations,
July 2021 in “European journal of pharmaceutics and biopharmaceutics” Nanoparticles sized between 470 and 750 nm are best for delivering substances like caffeine into hair follicles for absorption.
5 citations,
November 2021 in “Frontiers in Cell and Developmental Biology” Caffeine can damage hearing cells and affect hearing recovery after ear trauma.
1 citations,
July 2023 in “Cosmetics” The new shampoo effectively delivers caffeine to hair follicles to help keep hair, especially as people age.
46 citations,
October 2012 in “Dermatologic Clinics” Female pattern hair loss diagnosed by scalp appearance, treated with combined therapies and targeted approaches.
21 citations,
November 2012 in “Plastic and Reconstructive Surgery” Both genetic and lifestyle factors significantly affect female hair loss.
September 2014 in “Springer eBooks” Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.
61 citations,
January 2018 in “Cosmetics” Coffee silverskin may be a beneficial and safe ingredient for cosmetics, offering hydration, firmness, and potential hair growth benefits.
47 citations,
August 2016 in “Fitoterapia” Some herbs and their components might help treat hair loss by affecting various biological pathways, but more research and regulation are needed.
24 citations,
January 2020 in “International Journal of Molecular Sciences” Some plants with flavonoids may help treat hair loss and promote hair growth.
10 citations,
June 2019 in “International Journal of Cosmetic Science” Some plant-based chemicals may help with hair growth, but more research is needed to confirm their effectiveness.
2 citations,
July 2018 in “Elsevier eBooks” Some supplements may help with hair loss, but there's not enough strong evidence to recommend them without doctor advice.
1 citations,
March 2018 in “Dermatologie pro praxi” Most over-the-counter hair loss treatments lack strong evidence of effectiveness, except for minoxidil, which works but stops working if you stop using it.
3 citations,
April 2011 in “Expert Review of Dermatology” Mesotherapy lacks strong evidence for effectiveness and safety, and its ingredients are not FDA-approved for subcutaneous use.
130 citations,
August 2015 in “Experimental Dermatology” Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.
8 citations,
March 2020 in “Dermatologic Therapy” The new hair loss treatment kit was safe and improved hair growth without any adverse effects.
38 citations,
November 2005 in “Epilepsia” Levetiracetam is widely used and generally well-tolerated for treating idiopathic generalized epilepsies, with tiredness as the main side effect.
November 2022 in “Journal of Investigative Dermatology” The document concludes that a new method has been developed to test anti-aging substances on human skin, showing that these substances can reduce skin aging signs.
4 citations,
July 2023 in “Pharmaceutics (Basel)” Nanoparticle-based drug delivery to hair follicles is more effective when tested under conditions that match skin behavior.
September 2022 in “Polish Hyperbaric Research” Some treatments for hair loss, like finasteride, biotin, and minoxidil, can be effective, but their success varies by individual case.
February 2022 in “Scientia Pharmaceutica” Different hair loss treatment ingredients work well with TrichoTech™ vehicles for 3 to 6 months, making them good for use in hair treatments.
49 citations,
July 2004 in “Anesthesiology” The document concludes that more research is needed to understand how to treat muscle pain with drugs.
12 citations,
July 2017 in “Journal of cosmetic dermatology” Infrared thermography, especially with dermoscopy, improves accuracy in diagnosing active hair loss due to inflammation.
11 citations,
December 2014 in “Clinical Obstetrics and Gynecology” Obstetrician/gynecologists can diagnose and manage female hair loss with careful history taking and examination.
6 citations,
April 2020 in “Applied sciences” Hair growth medium helps heal wounds and regrow hair in mice.
6 citations,
December 2015 in “International journal of nanomedicine” Using sonophoresis can make it harder for certain drug-loaded liposomes to get through the skin.
2 citations,
January 1997 in “Principles of Medical Biology” Drug metabolism affects how long a drug works, its interactions, activation, and toxicity, and is influenced by genetics, diet, illness, and other drugs.