Improvement of Alopecia and Decreases in Hair Cortisol and Dihydrotestosterone Concentrations After the Topical Use of Plant Extracts in Men With Androgenetic Alopecia
August 2021
in “
Asian Journal of Pharmaceutical and Clinical Research
”
New to Hydrocortisone? There is a guide in the encyclopedia. Read the guide → Studysummary In this randomized trial, a solid shampoo formulated with plant extracts was more effective than placebo in improving androgenetic alopecia and reducing hair cortisol and DHT concentrations in men.
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The study, a randomized, placebo-controlled, single-blind trial with 48 men in the treatment group and 52 in the placebo group, found that a solid shampoo containing six plant extracts significantly improved hair shaft thickness and hair density in men with androgenetic alopecia (AGA). After 4 months, hair cortisol and dihydrotestosterone (DHT) concentrations in the treatment group were reduced to control levels, while salivary cortisol and DHT levels remained unchanged. The findings suggested that the plant extracts could prevent hair loss, promote hair growth, and reduce hair cortisol and DHT concentrations without affecting salivary steroid levels.
