A Summary of Pre-Clinical and Clinical Evidence for Cannabinoid Hair Follicle Effects

The document reviews evidence suggesting that cannabinoids, particularly CBD, THCV, and CBDV, may promote hair growth and could be beneficial in treating androgenetic alopecia (AGA). It highlights the role of the endocannabinoid system in hair follicle function and how these cannabinoids interact with receptors that influence hair growth. Clinical trials have shown promising results, with one trial reporting a 93.5% increase in hair count with CBD alone, and another showing a 164% increase with a hemp extract containing CBD, THCV, CBDV, and menthol over six months. The document also notes the safety of topical hemp extract applications and suggests that cannabinoids could work synergistically with current treatments like minoxidil and finasteride. However, the document does not specify the number of participants in these trials.