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Keratin hydrogels from human hair show promise for tissue engineering and regenerative medicine.

NIPP1 is important for healthy skin and could help treat skin inflammation.

A new mRNA variant of the SCF gene in sheep skin produces a shorter, different protein.

Mutations in three genes cause Uncombable Hair Syndrome, leading to frizzy hair that can't be combed flat.

Cidea is essential for proper lipid storage and secretion in sebaceous glands, affecting skin and hair health.

Edar signaling is crucial for proper hair follicle development and function.

Intermediate filaments are crucial for cell differentiation and stem cell function.

Enzymes called PADIs play a key role in hair growth and loss.

Human hair is made up of different keratins, some strong and some weak, with specific types appearing at various stages of hair growth.

TGM3 is important for skin and hair structure and may help diagnose cancer.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

Baricitinib and its combination with lonafarnib improve fat cell formation in certain genetic disorders.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

PAD3 plays a key role in hair and skin protein structure and may be linked to skin diseases.

Targeting the Smoothened receptor shows promise for treating certain cancers.

Small proline-rich proteins and trichohyalin help make epithelial tissues tougher and more flexible.

Nonpalmoplantar skin cells can be made to express keratin 9 by interacting with palmoplantar fibroblasts.

Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.

A specific gene mutation causes long hair in Angora rabbits.

The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.

Regulating cell death in hair follicles can help prevent hair loss and promote hair growth.

FKBP10 and FBN2 are key proteins for hair growth in cashmere goats.

CRISPR/Cas9 has improved precision and control but still faces clinical challenges.

The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

VDR regulation varies by tissue and is crucial for its biological functions.

Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.

RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.