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This study found that Lepidium sativum leaf extract significantly downregulated VEGF, TNF-α, and SRD5A2 gene expressions in HaCaT cells, suggesting potential benefits for inflammatory and androgen-dependent skin disorders.

This review discusses the relationship between gut microbiota and polycystic ovarian syndrome (PCOS), including its potential mechanisms and the role of alterations in microbiome composition on PCOS pathophysiology.

This study found that patients with alopecia areata had a higher frequency of the AB+ blood group compared to healthy controls.

This article provides an overview of diagnosing Cushing's syndrome, emphasizing the importance of assessing clinical signs and the appropriate use of first-line biochemical screening.

This study observed that COVID-19-related stress and fear were potentially associated with an increased occurrence of hair diseases like telogen effluvium, alopecia areata, and seborrheic dermatitis among medical students in Bangladesh.

Inhibiting PGD2 and using dermal papilla cells may improve skin and hair regeneration.

Innovative methods are reducing animal testing and improving biomedical research.

This case report describes a 16-year-old girl initially diagnosed with chronic telogen effluvium, later reassessed with Ludwig Stage 1 androgenetic alopecia, for which she began spironolactone treatment.

This study concluded that finasteride treatment did not adversely affect bone development or density in male rats, suggesting selective DHT deficiency is not harmful to the skeleton.

This case study reported an improvement in lower limb edema for a patient with type 2 diabetes mellitus after starting dulaglutide treatment, suggesting a potential role of the drug in sodium retention disorders.

In this Phase II study, BAY 43–9006, taken orally for renal cell carcinoma, stabilized disease in 30% of patients, with 40% responding positively, although the targets remain unclear.

This review examines recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia, highlighting two major genetic risk loci, but does not report new clinical findings.

This review summarizes common skin-related side effects of BRAF inhibitors and immunotherapy in advanced melanoma treatment, reporting no new clinical findings, and emphasizes consensus management to improve patient outcomes.

This review discusses the mechanisms of skin aging, highlighting the roles of stem/progenitor cells, genetic and environmental factors, and suggests potential for cell-based therapies, but reports no new experimental findings.

This study found that various reduced folates effectively penetrated an in vitro skin model, promoted cell proliferation and migration, and may enhance wound healing, suggesting potential for topical treatment in skin conditions.

This study explored the relationships between virus susceptibility to infection and several factors, finding that higher heat tolerance and larger virus size correlated positively with infection susceptibility, while high humidity and higher mutation rates correlated inversely among eight RNA viruses, including SARS-CoV-2 and influenza.

This study observed that patients with alopecia areata had significantly different levels of oxidative stress markers SOD and MDA compared to controls.

This study found that Shh from neurons signals to Gli1-expressing cells in the hair follicle, cultivating a niche where these bulge cells can potentially transform into epidermal stem cells in wound healing.

This review discusses the classification and diagnosis of pregnancy-related skin conditions and reports no new clinical findings.

This review discusses recent strategies targeting the neuroactive steroid biosynthetic pathway to enhance neurosteroidogenesis, highlighting their potential benefits for neurodegenerative and neuropsychiatric diseases, but reports no new clinical findings.

This pilot study suggests injecting platelet-derived growth factors into the scalp may offer some clinical benefits for androgenetic alopecia, though further randomized trials are needed for confirmation.

In this study, germacrone from Curcuma aeruginosa showed anti-androgenic effects by inhibiting 5α-reductase, suggesting its potential as a lead compound for treating androgen-dependent disorders.

This review discusses the embryonic origins and characteristics of various stem cell populations in the skin, but it provides no new experimental results.

This review addresses the role of skin-resident adult stem/progenitor cells in skin homeostasis, disease, and cancer development, and reports no new research results.

This study found that human hair follicle dermal cells, specifically dermal sheath cells, can serve as an alternative and potentially superior cell source for constructing the dermal component of bioengineered skin in both in vitro and in vivo settings.

In this study, researchers found that a polyphenolic extract from Annurca apples, high in procyanidin B2, increased hair growth, density, and keratin content in healthy subjects after 2 months of use, and stimulated keratin biosynthesis in vitro.

This review discusses genome-wide association studies in dermatology, noting that variants linked to risk for 10 skin complex diseases have been identified, with potential implications for diagnostics and management; it reports no new clinical results.

Testicular microlithiasis may increase the risk of testicular cancer and patients with it should be closely monitored.

This review discusses the dermatologic care of transgender individuals and highlights the need for more quantitative research to improve clinical understanding and support future studies.

This study found that women with female pattern hair loss had increased 5α-reductase isozymes and decreased aromatase mRNA levels, potentially affecting their response to treatment.