Evaluation of Antioxidant and Oxidant Status, Including Levels of Malondialdehyde and Superoxide Dismutase, in the Indian Population with Alopecia Areata

    Krishna Chaitanya Paleti, Payasvi Sachdeva, Krishna Chaitanya Paleti
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    TLDR Oxidative stress is important in causing alopecia areata.
    The study investigated the oxidative stress in 150 patients with alopecia areata (AA) compared to 150 controls. It focused on the levels of Malondialdehyde (MDA) and Superoxide Dismutase (SOD), which are indicators of oxidative stress. The results showed a highly significant difference in the levels of SOD and MDA between the AA patients and the control group (P<0.0001), suggesting that oxidative stress plays a significant role in the pathogenesis of alopecia areata.
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