March 2024 in “Intisari Sains Medis” This narrative review reported that intradermal injection of autologous platelet-rich plasma showed objective improvement and increased patient satisfaction in treating periorbital wrinkles, though the authors noted the need for further rigorous studies to confirm these findings.
January 2024 in “International Journal of Dermatology Research” In this study, platelet-rich plasma therapy was observed to provide better improvement in hair regrowth for alopecia areata patients than intralesional triamcinolone acetonide, as measured by lower SALT scores.
November 2023 in “Research Square (Research Square)” This double-blinded randomized clinical trial found that combining topical vitamin D analog (calcipotriol) and intra-lesion PRP led to a greater reduction in hair loss severity in alopecia areata patients compared to either treatment alone, with significant improvements observed across all groups.
August 2023 in “Research Square (Research Square)” This study found that among patients with inflammatory bowel disease, those with the NUDT15 mutation had a reduced tolerance for thiopurine dosage over the long term and were more likely to require hospitalization and surgery compared to those without the mutation.
This abstract suggests that cost barriers limit the application of standard aesthetic procedures in developing countries, while exploring platelet-rich plasma as a potentially safer and less invasive option in geriatric aesthetics. Detailed results were not reported.
This article introduces geriatric aesthetics and discusses the potential of platelet-rich plasma as a cost-effective solution in developing countries, but reports no new clinical results.
July 2021 in “Medical journal, Armed Forces India” This study reported that using platelet-rich plasma as an intraoperative holding solution significantly improved hair density and follicular growth in hair restoration surgery for androgenetic alopecia.
March 2019 in “European archives of medical research” In this study, PRP injections were found to improve hair density and quality in patients with androgenetic alopecia, with a significant reduction in hair loss and high patient satisfaction after three treatment sessions over several months.
January 2023 in “Annali di stomatologia” This review traces the development and application of Platelet-rich Plasma in regenerative medicine, emphasizing its role in tissue healing and bone regeneration, but reports no new clinical results.
130 citations
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September 2018 in “Cell Reports” This study found that macrophages play a crucial role in nerve regeneration by regulating Schwann cell dynamics and remyelination, with Gas6 identified as a key factor in this process.
113 citations
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July 2015 in “Journal of Cosmetic Dermatology” This review discusses the cosmetic applications of platelet-rich plasma in dermatology, highlighting its potential benefits and the need for more controlled studies.
66 citations
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June 2015 in “Aesthetic Plastic Surgery” This review of 47 studies indicates that platelet preparations may significantly enhance cellular activity, wound healing, and facial aesthetic outcomes in facial plastic surgery, though potential publication bias should be considered.
65 citations
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April 2020 in “International Journal of Molecular Sciences” This review indicates that most studies reported positive effects of platelet-rich plasma injections for treating androgenic alopecia, with no major side effects, suggesting it may be a safe alternative to Minoxidil and Finasteride.
55 citations
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September 2017 in “Journal of Cosmetic Dermatology” This review discusses the diverse applications of platelet-rich plasma in aesthetic dermatology and assesses the existing literature on its effectiveness, reporting no new clinical results.
53 citations
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June 2017 in “Skin appendage disorders” This review suggests that platelet-rich plasma may be effective in increasing hair density in patients with androgenetic alopecia, but more research is needed to determine the best treatment protocol.
27 citations
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July 2017 in “Facial Plastic Surgery” This review examines the growing evidence for using platelet-rich plasma in aesthetic procedures such as hair restoration and skin rejuvenation but reports no new clinical results.
20 citations
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June 2010 in “Genes and Immunity” This study found distinct gene expression patterns in the blood of alopecia areata patients, suggesting involvement of immune processes and new pathways like Wnt signaling and apoptosis in disease pathogenesis.
19 citations
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August 2019 in “Seminars in Plastic Surgery” This review explains the biology and preparation of platelet-rich plasma and discusses its clinical applications in plastic surgery, but reports no new findings.
16 citations
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March 2020 in “Facial Plastic Surgery Clinics of North America” The authors concluded that platelet-rich plasma (PRP) shows promising potential as a safe treatment for hair restoration in androgenic alopecia, though further research is needed to refine its use and confirm long-term effects.
15 citations
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October 2020 in “Journal of Investigative Dermatology Symposium Proceedings” This review discusses the potential use of platelet-rich plasma for treating alopecia areata but reports no new experimental findings, noting the need for standardized protocols and larger studies to evaluate its efficacy.
15 citations
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December 2013 This study found that in men with androgenic alopecia, moderate to severe cases were associated with the AA genotype of rs1160312, blood vanadium concentrations, and regular consumption of soy bean drinks.
13 citations
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January 2020 in “Experimental Dermatology” This pilot clinical trial suggests that platelet-rich plasma (PRP) treatment may increase hair density in patients with androgenetic alopecia, though outcomes varied between patients.
12 citations
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March 2018 in “Bioengineering” This review discusses the use of non-transfusional hemocomponents in surgical procedures for tissue regeneration and reports no new empirical findings.
11 citations
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May 2021 in “Journal of Cosmetic Dermatology” This review discusses the potential use of platelet-rich plasma for treating melasma, suggesting its effectiveness but noting the need for more extensive studies to confirm these findings.
10 citations
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August 2020 in “Journal of Bioscience and Bioengineering” This study reports that using activated platelet-rich plasma releasate in the preparation of bioengineered hair follicle germs enhanced follicular gene expression and significantly improved hair regeneration in vitro.
8 citations
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October 2019 in “Immunological investigations” This study suggests that the rs2075876 variant in the AIRE gene may significantly increase susceptibility to alopecia areata in the examined male population.
5 citations
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May 2019 in “Archives of Dermatological Research” This study reported that narrowband UVB treatment significantly increased WNT7B, WNT10B, and TCF7L2 gene expression in lesional skin of psoriasis patients, suggesting these genes may play a role in psoriasis pathogenesis.
5 citations
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January 2013 in “Otorhinolaryngology clinics : an international journal” This review discusses the use of platelet-rich plasma in cosmetic surgery, highlighting its expanding applications and promising potential in aesthetic treatments, but reports no new empirical findings.
3 citations
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March 2023 in “National Journal of Health Sciences” This article reviews the potential of platelet-rich plasma therapy in managing diabetic foot ulcers but reports no new clinical findings, highlighting the need for further controlled trials to evaluate its effectiveness.
3 citations
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December 2019 in “Journal of Cosmetic and Laser Therapy” This study found that plasma rich in growth factors showed promising results for increasing hair number and thickness in androgenic alopecia patients, with better outcomes after multiple injections.