Standardization of Plasma Rich in Growth Factors and Its Effects on Androgenic Hair Loss

    December 2019 in “ Journal of Cosmetic and Laser Therapy ”
    Mehdi Zolfaghari, Mohyedin Barzegar, Vahid Amiri, Mehdi Allahbakhshian Farsani, Shaboo Jesri, Abdollah Kiani Harchegani, Mohammad Hossein Mohammadi
    Image of study
    TLDR PRGF treatments increased hair number and thickness in people with hair loss, with more injections leading to better results.
    The study from 2019 examined the impact of Plasma Rich in Growth Factors (PRGF) on androgenetic alopecia (AGA) in 13 patients. Participants were divided into two groups, with one receiving a single PRGF injection and the other receiving three injections over three months. Results indicated that both groups saw improvements in hair number and thickness, with the single injection group experiencing a 9-54% increase in hair number and an 11-76% increase in hair thickness, while the three-injection group saw an average increase of 211% in hair number and 221% in hair thickness. No serious adverse effects were reported, though some minor, self-limited side effects like edema, itching, and erythema occurred, resolving within 24 hours. The study concluded that PRGF is a promising treatment for AGA, but highlighted the need for further research with larger sample sizes and longer follow-up periods to establish a standardized treatment protocol.
    Discuss this study in the Community →

    Research cited in this study

    11 / 11 results

    Related Community Posts Join

    6 / 146 results

      community New and Interesting HairLoss Studies/Papers/Reviews

      in Treatment  44 upvotes 4 years ago
      Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

      community Comparison of options: topical vs medication

      in Female  1 upvotes 5 months ago
      A user diagnosed with AGA is seeking advice on hair loss treatments, comparing topical Minoxidil, Spironolactone, and Finasteride to oral medications and natural methods like dermastamping, PRP, and LED light. They are concerned about side effects and effectiveness, especially given their existing fatigue.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  138 upvotes 9 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 3 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

    Related Research

    10 / 10 results