61 citations,
September 2008 in “Stem Cells” Most hair follicle stem cells do not protect their DNA by dividing it unevenly.
11 citations,
September 2020 in “OncoTargets and Therapy” Dihydrotestosterone increases growth and spread of human brain cancer cells, and blocking its formation might help treat this cancer.
26 citations,
December 2006 in “Endocrinology” A cream with a specific hormone blocker increases hair growth in mice.
7 citations,
September 2017 in “Scientific Reports” Mice with too much sPLA₂-IIA have hair loss and poor wound healing due to abnormal hair growth and stem cell depletion.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.
Skin cells can naturally limit the growth of cancerous changes by balancing cell renewal and differentiation.
39 citations,
May 2010 in “Stem Cells” Ephrins slow down skin and hair follicle cell growth.
10 citations,
September 1997 in “Molecular carcinogenesis” Mirex seems to promote a unique group of skin cells different from those affected by another tumor promoter, TPA.
9 citations,
January 2006 in “Cutaneous and ocular toxicology” L-cystine, D-pantothenat, and miliacin together significantly boost keratinocyte growth and metabolism.
December 2020 in “한국인그리에학회지” Astringent persimmon fruit extract may help increase hair length and coverage without increasing the number of hair follicles.
22 citations,
January 2011 in “Indian Journal of Dermatology/Indian journal of dermatology” Cow placenta extract may help hair grow by increasing a growth factor but is less effective than minoxidil.
29 citations,
March 2012 in “Stem Cell Research & Therapy” Some stem cells in the body rarely divide, which could help create better treatments for diseases and aging.
20 citations,
August 2014 in “PloS one” MED1 affects skin wound healing differently in young and old mice.
4 citations,
January 2011 in “Cell stem cell” Hair follicle stem cells can return to their original niche and help regenerate hair.
The balance between cell renewal and differentiation controls the growth of cancerous cells in mouse skin.
6 citations,
January 2020 in “Skin Pharmacology and Physiology” HIF-1α stimulators, like deferiprone, work as well as popular hair loss treatments, minoxidil and caffeine, in promoting hair growth.
24 citations,
September 2014 in “Drug Delivery” Using microneedles before applying eflornithine cream can make it more effective at stopping hair growth.
12 citations,
December 2009 in “Amino Acids” Putting α-methylspermidine on mouse skin can start hair growth.
3 citations,
April 2019 in “bioRxiv (Cold Spring Harbor Laboratory)” Beta-caryophyllene, found in essential oils, helps wounds heal better in multiple ways.
17 citations,
July 2013 in “Amino Acids” Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.
293 citations,
November 2011 in “Nature” The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.
2 citations,
July 2017 in “Oncology Letters” Lacking cyclin D3 reduces skin cancer growth without affecting normal skin cell growth.
January 2025 in “PLoS ONE” ING5 is crucial for stem cell maintenance and preventing certain cancers.
81 citations,
February 2014 in “EMBO molecular medicine” Activating Nrf2 in skin cells causes skin disease similar to chloracne in mice.
24 citations,
November 2023 in “Nature” The extracellular matrix affects where tumors can start in the body.
160 citations,
January 2014 in “Seminars in cell & developmental biology” Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.
Mealworm protein helps fat cell development and may aid in metabolic health and hair growth.
33 citations,
July 2007 in “Journal of cell science” Miz1 is essential for proper hair structure and growth.
6 citations,
April 2012 in “PloS one” The local environment is crucial for cell development in the tongue.
92 citations,
November 2006 in “Proceedings of the National Academy of Sciences of the United States of America” BMP signaling controls hair follicle size and cell growth by affecting cell cycle genes.