23 citations
,
June 1950 in “American journal of diseases of children” This article discusses the interest in folic acid antagonists for leukemia treatment, noting their potential mechanism of interfering with cellular growth, but reports no new clinical results.
11 citations
,
November 2009 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study found that bolandiol increased lean body mass and bone mineral density in castrate adult male rats, exhibiting tissue selectivity and acting through multiple receptor pathways with less potency compared to other androgens.
May 2014 in “Annals of Plastic Surgery” The book is highly praised as an essential resource for plastic surgeons, despite minor gaps.
195 citations
,
February 2007 in “The Journal of Clinical Endocrinology and Metabolism” In this study, administering 5alpha-reductase inhibitors reduced dihydrotestosterone levels and was associated with mild, reversible decreases in semen parameters in healthy men.
5 citations
,
April 2025 in “Journal of Functional Biomaterials” In this study, the addition of A-PRF+ to surgical protocols significantly improved bone healing and implant stability when combined with biomaterials, suggesting it as a viable option for patients concerned about using human- and animal-derived biomaterials.
August 2024 in “Quality in Sport” This review highlights the positive effects of platelet-rich plasma in aesthetic and regenerative medicine, particularly for skin rejuvenation, anti-aging, hair reconstruction, and wound healing, but it reports no new clinical results.
December 2017 in “Elsevier eBooks” This study suggests that unliganded vitamin D receptors in mice may cause more severe skeletal and mineral ion defects than VDR-null conditions, and vitamin D analogues may restore function in specific VDR mutations.
37 citations
,
January 2019 in “Food science & nutrition” This review summarizes various effects of bergamot components on multiple health conditions in humans and animals but reports limitations in their use for stress and anxiety relief in aromatherapy.
14 citations
,
July 2021 in “Bioscience Reports” In this study, activation of Tgr5 was found to improve alopecia areata and bone microstructure in mice by down-regulating the JAK1-STAT3 signaling pathway.
46 citations
,
May 2021 in “Stem Cell Research & Therapy” This study found that strontium ranelate promotes cartilage regeneration in rats by enhancing chondrogenic differentiation of bone mesenchymal stem cells while inhibiting the Wnt/β-catenin signaling pathway.
10 citations
,
June 2019 in “Aesthetic Plastic Surgery” This study observed that amniotic allografts provided similar aesthetic improvements with less downtime and quicker results compared to PRP treatment for midface volume enhancement.
6 citations
,
June 2024 in “Gels” In this study, researchers used 3D printing combined with cryogenic crosslinking to develop gelatin/oxidized alginate scaffolds and found that adding 5% hydroxyapatite improved mechanical properties and osteogenic effects, enhancing bone tissue regeneration, though 10% hydroxyapatite offered no additional osteogenic benefits and reduced shape fidelity.
4 citations
,
January 2021 in “International Journal of Medical Sciences” This study suggests that miR-182 may play an essential role in hallux valgus development by regulating FGF9 expression, indicating a potential therapeutic target for its treatment.
3 citations
,
May 2015 in “Journal of archives in military medicine” This review discusses the regenerative potential of platelet-rich plasma in military medicine applications, finding inconsistent but generally favorable outcomes across various conditions, including tendon and bone injuries.
2 citations
,
September 2020 This Mendelian randomization study reports that lifelong increased free testosterone in males was associated with improved bone mineral density and body composition but increased risks of prostate cancer, hypertension, and several other conditions.
This study found that activating BMP signaling in rodent and primate models significantly promotes nail and digit regeneration after amputation by enhancing the role of specific nail stem cells, though extreme proximal amputation only permitted partial regeneration without bone reconstruction.
December 2024 in “Advanced Composites and Hybrid Materials” This study provides a comprehensive review of the use of electrospinning technology to create 3D porous structures for bone implants, emphasizing the synergy between biomedicine and materials science necessary for developing orthopedic materials.
This study using Mendelian randomization suggests lifelong increased free testosterone in males may have beneficial effects such as increased bone mineral density and decreased body fat, but also increased risks of prostate cancer and hypertension.
1 citations
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November 2024 in “Journal of Cutaneous and Aesthetic Surgery” This study highlights fat grafting and nanofat as promising options for treating dark circles, offering benefits in improving both volume and skin quality through a single-stage procedure with long-lasting outcomes.
January 2026 in “Burns & Trauma” This review synthesizes evidence on how RNA modifications affect wound healing, particularly in skin, bone, and corneal injuries, emphasizing potential therapeutic strategies for burns and trauma in relation to these cellular processes.
December 2024 in “Molecules” This study observed that bovine milk-derived exosomes can alleviate intestinal inflammation, improve cognitive function, support nervous system regeneration, promote bone health, and benefit skin health, although further research is needed to fully understand their mechanisms and potential clinical applications.
November 2023 in “Biomolecules” In this study involving genetically modified rats, researchers observed that specific mutations in the vitamin D receptor affect calcium levels and bone formation, emphasizing the receptor's role in maintaining healthy bone density and its importance in regulating hair cycle and skin health.
271 citations
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September 2008 in “Nutrition reviews” This study identified new dietary ligands for the human vitamin D receptor, including curcumin and gamma-tocotrienol, which may influence its biological functions.
140 citations
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August 2011 in “Biomaterials” This study observed that keratose, derived from human hair, integrated well in mouse tissue and remodeled with collagen, suggesting potential as a non-toxic biomaterial for regenerative applications.
79 citations
,
October 2015 in “Journal of Dermatological Treatment” This review assesses the use of platelet-rich plasma in dermatology and concludes that while there may be modest benefits for certain conditions, more evidence is needed before it can be widely recommended.
77 citations
,
May 2012 in “Expert Opinion on Emerging Drugs” New treatments for male hypogonadism are effective and should be personalized.
76 citations
,
January 2017 in “World Journal of Stem Cells” This review discusses the potential applications of adipose-derived stromal cells for treating conditions like colitis, liver failure, and more, without presenting new clinical results.
55 citations
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August 2024 in “Heliyon” This review article highlights recent progress and challenges in stem cell transplantation for regenerative medicine, emphasizing its potential in tissue repair for conditions like bone and cartilage injuries, neurological disorders, and blood diseases, while stressing the importance of overcoming current obstacles for future advancements.
26 citations
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December 2020 in “Cleveland Clinic Journal of Medicine” This review examines the roles of androgens in women's health and provides recommendations for androgen therapy but reports no new results.
23 citations
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June 2015 in “Oncology Letters” This study reported that adipose-derived stem cell-conditioned medium demonstrated anti-tumorigenic effects on B16 melanoma cells both in vitro and in vivo, indicating potential for future melanoma treatment.