81 citations,
January 2003 in “The FASEB Journal” Follistatin helps hair growth and cycling, while activin prevents it.
75 citations,
September 2015 in “Acta biomaterialia” Alkylation of human hair keratin allows for adjustable drug release rates in hydrogels for medical use.
71 citations,
February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
68 citations,
April 2012 in “Journal of Investigative Dermatology” The conclusion is that Fgf18 and Tgf-ß signaling could be targeted for hair loss treatments.
65 citations,
April 2000 in “The Laryngoscope” Clotrimazole, miconazole, and tolnaftate are likely safe, but gentian violet is risky.
47 citations,
May 2012 in “Wiley Interdisciplinary Reviews-Developmental Biology” The conclusion is that understanding how feathers and hairs pattern can help in developing hair regeneration treatments.
44 citations,
June 2017 in “The EMBO Journal” LPA3 signaling in the uterus is crucial for placental formation and fetal development.
41 citations,
April 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” Deleting MED1 in skin cells causes hair loss and skin changes.
37 citations,
May 2018 in “Frontiers in physiology” Certain RNA molecules are important for the development of wool follicles in sheep.
32 citations,
January 2017 in “Orphanet journal of rare diseases” FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.
29 citations,
April 2020 in “Biomolecules” The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.
25 citations,
May 2017 in “InTech eBooks” Catalytic antibodies are early indicators and active participants in the development of systemic lupus erythematosus.
24 citations,
September 2019 in “Experimental cell research” BMP2 helps hair follicle stem cells become specialized by increasing PTEN, which causes autophagy.
23 citations,
December 2020 in “Frontiers in Cell and Developmental Biology” Gene network oscillations inside hair stem cells are key for hair growth regulation and could help treat hair loss.
21 citations,
June 1990 in “British Journal of Dermatology” Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.
19 citations,
August 2019 in “Expert Opinion on Therapeutic Targets” New treatments for hair loss may target specific pathways and generate new hair follicles.
19 citations,
November 2017 in “General and comparative endocrinology” BMP2 and BMPR-IA may stop hair growth while Noggin may encourage it in yak skin.
19 citations,
April 2015 in “Developmental Dynamics” The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.
18 citations,
April 2014 in “Stem cells” The study found stem cells in minor salivary glands that can differentiate and are involved in tumor formation when exposed to tobacco.
18 citations,
November 2013 in “Molecules and Cells” New culture method keeps human skin stem cells more stem-like.
18 citations,
December 2009 in “Canadian Journal of Animal Science” The BMP2 gene is more active in the early growth phase of Cashmere goat hair and may affect hair regeneration and textile production.
17 citations,
February 2018 in “British Journal of Oral & Maxillofacial Surgery” Forehead reduction and orbital contouring are important for satisfactory facial feminization in transgender females, with high satisfaction and low long-term problems.
16 citations,
April 2021 in “Frontiers in Cell and Developmental Biology” New hair follicles could be created to treat hair loss.
15 citations,
June 2015 in “Human Cell” Spheroid culture in agarose dishes improves survival and nerve cell growth in thawed human fat-derived stem cells.
14 citations,
April 2016 in “Cell Transplantation” Neural stem cell extract can safely promote hair growth in mice.
13 citations,
March 2020 in “Genes” Disrupting the FGF5 gene in rabbits leads to longer hair by extending the hair growth phase.
13 citations,
January 2018 in “Cellular Physiology and Biochemistry” Fat-derived stem cells can help protect and repair skin stem cells from aging caused by UV light.
12 citations,
May 2019 in “Stem cell reviews” Fetal-maternal stem cells in a mother's hair can help with tissue repair and regeneration long after childbirth.
10 citations,
December 2018 in “Journal of animal physiology and animal nutrition” Heat stress reduced hair growth and affected related genes in rex rabbits.
9 citations,
July 2001 in “Cell” Cells from certain embryo parts can induce head formation in another embryo, involving complex signaling pathways.