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In this study using a transgenic mouse model, Id2 overexpression in hair follicle stem cells prolonged quiescence by affecting gene expression, partly independent from BMP signaling.

This case report introduces a novel instance of long-term cutaneous neoplastic degeneration following artificial hair implantation, a previously unreported complication in such procedures.

This study found that scalp basal cell carcinomas do not appear to behave more aggressively than other types, despite suggestions in the literature.

This study found that human mesenchymal stromal cells derived from hair follicle dermal sheath showed promising growth and wound-healing properties in vitro and in diabetic mice, suggesting potential for therapeutic use.

This review examines cell-based therapies for limbal stem cell deficiency, highlighting epidermal and hair follicle-derived stem cells as promising candidates for future clinical trials, but reports no new clinical findings.

This study found that neural crest-derived hair follicle cells in mice can differentiate into osteoblast-like cells, suggesting a potential application for bone regenerative therapies.

This study found that UVB irradiation alters skin stem cell niches leading to signs of photoaging, which may be reversed by adipose-derived stem cells through BMP4 pathway modulation and niche remodeling.

This review discusses the use of zebrafish larvae as an alternative model for studying ototoxicity, facilitating large-scale screening for otoprotective compounds, but reports no new clinical results.

This review discusses the use of human mesenchymal stem cells (hMSCs) for treating skin diseases and suggests they show promise for improving conditions like wounds and scleroderma, but more research is needed due to varied study designs and endpoints.

The study suggests that a 3D culture system using the RAD16-I peptide scaffold can help restore the original phenotype of hair follicle dermal papilla cells and support their osteogenic and adipogenic differentiation.

In this study, myofibroblasts in rat cutaneous fibrosis were characterized by expressions of vimentin, α-SMA, and Thy-1, and may derive from pericytes or perifollicular dermal sheath cells.

This study found that exosomes derived from antler stem cells significantly enhanced wound healing speed and quality in rats, including better skin regeneration and collagen distribution, outperforming exosomes from bone marrow stem cells, and suggesting potential clinical applications.

This study found that androgens downregulate BMP2 in dermal papilla cells, inhibiting hair follicle stem cell differentiation, while BMP2 addition may restore hair lineage differentiation through the Wnt/β-catenin pathway.

This review discusses the potential of mesenchymal stromal cell secretome therapies for facial nerve palsy, emphasizing their standardization advantages over cell transplantation, but provides no new clinical results.

This study focused on the ultrastructural and immunohistochemical aspects of dermal mast cells in systemic mastocytosis and their interaction with the epidermal melanin unit.

This review examines the mechanisms, recent findings, and strategies to enhance mesenchymal stem cells' therapeutic effects in skin wound healing, but reports no new research results.

In this study, researchers assessed the efficacy of Trichosera® hair serum, containing mesenchymal stromal cells conditioned media, among 40 healthy Indian volunteers, finding significant improvements in hair growth rate, hair density, scalp condition, and reduction in hair fall without notable adverse effects.

This study found that BMP-2 activates Dlx3 gene transcription in murine keratinocytes by binding with Smad1/Smad4, suggesting a mechanism for BMP signaling's role in skin and hair follicle regulation.

This article describes the skin changes seen in acute and chronic graft-vs-host reactions after bone marrow transplantation, highlighting the potential for early recognition due to the visibility of these changes, but reports no new clinical results.

This study observed that isoproterenol directs hair-follicle-associated pluripotent stem cells to differentiate into cardiac muscle cells in large numbers, forming tissue sheets of beating heart muscle cells in culture.

This paper presents a protocol for differentiating human-induced pluripotent stem cells into keratinocyte progenitor cells and keratinocytes, suggesting potential applications for hair follicle restoration and burn or ulcer therapy.

This review discusses advancements in stem cell therapy for cutaneous radiation syndrome, highlighting the potential of various stem cell sources to improve wound healing and reduce symptoms, but reports no new clinical results.

This review examines a study showing that the balding scalp in men with androgenetic alopecia retains stem cells but lacks certain progenitor cells, suggesting new targets for future therapies; it reports no clinical results.

In this study, researchers found that treating dermal papilla cells with synovial fluid and laser photobiomodulation increases the expression of chondrocyte marker genes, indicating potential promotion of chondrogenic differentiation.

This study found that FPR2 knockout mice experienced excessive hair loss and abnormal hair follicle structures, suggesting FPR2's protective role in hair regeneration through stem cell activity regulation.

This review explores the potential of mesenchymal stem cells in skin regeneration and rejuvenation, highlighting their ability to modulate immune response and enhance extracellular matrix strength but does not provide new clinical evidence.

Using mouse hair follicle organoids, this study demonstrated that BMP4 plays a key role in controlling hair follicle coloration and growth, as well as directing Nestin-positive stem cells towards becoming melanocytes, the pigment-producing cells responsible for hair color.

In this study, Panax ginseng extract and its ginsenosides were found to stimulate the proliferation of hair-related cells and promote the transition from the telogen to the anagen phase, enhancing hair-shaft growth by suppressing BMP4 expression in human dermal papilla cells.

This study reviews the regulatory mechanisms and molecular processes governing stem cell activity in hair follicles, highlighting their roles in hair regeneration and potential implications for treating hair and skin disorders.

This study found that in hairpoor mice, disruptions in hair follicle stem cell quiescence and signaling pathways lead to disturbed hair cycles, which may help explain alopecia development in Marie-Unna Hypotrichosis patients.