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TPA is about 50 times more effective at promoting tumors than MZ.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

Mutations in Gasdermin A3 cause skin inflammation and hair loss by disrupting mitochondria.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Japanese women typically start experiencing hair loss after 40, with reduced hair density and thickness being the main factors.

Certain mice without specific receptors or mast cells don't lose hair from stress.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

Hair grays due to oxidative stress and fewer functioning melanocytes.

Vervet monkeys show physical changes like hair loss and scrotal color changes due to stress or nutrition issues.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

Four genetic risk spots found for hair loss, with WNT signaling involved and a link to curly hair.

The HR protein's role as a repressor is essential for controlling hair growth.

The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.

The 190-kbp domain contains all human type I hair keratin genes, showing their organization and evolution.

Toxic epidermal necrolysis is a severe skin condition often caused by drugs, with complex treatment and a high risk of death, but survivors usually heal without scars.

Antioxidants may help fight oxidative stress linked to autoimmune skin diseases.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

The protein folliculin, involved in a rare disease, works with another protein to control how cells stick together and their organization, and changes in this interaction can lead to disease symptoms.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

Mercuric triflate is an effective catalyst for various organic reactions, working well at room temperature with high yields.

Human hair follicles can regenerate after removal, but with low success rate.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

mTOR signaling helps activate hair stem cells by balancing out the suppression caused by BMP during hair growth.

HFMs can help study hair growth and test potential hair growth drugs.

Fetal skin cells from a cell bank heal wounds faster and with less scarring than adult cells.

The p53 protein helps control hair follicle shrinking by promoting cell death in mice.

Electrospun nanofibers show promise for enhancing blood vessel growth in tissue engineering but need further research to improve their effectiveness.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.