September 2025 in “Frontiers in Genetics” This study developed a non-invasive, partially automated protocol for extracting high-quality DNA from hair follicles of marmosets, significantly reducing chimerism rates compared to blood, and proving reliable for whole genome sequencing in low-input DNA scenarios.
April 2025 in “Research Square (Research Square)” This study found that microinfusion of minoxidil into the scalp was associated with a reduction in diastolic blood pressure, indicating systemic absorption of the drug.
February 2025 in “Clinical Cosmetic and Investigational Dermatology” This study used Mendelian randomization to explore associations between 1400 blood metabolites and female-pattern hair loss, finding 23 metabolites and 4 metabolic ratios linked to the condition, while identifying fructose/mannose metabolism as a significant pathway.
July 2024 in “Chinese Medical Journal” This study concluded that ACT injections, alone or combined with finasteride, have significant therapeutic effects and safety in treating androgenic alopecia, with promising clinical potential.
June 2024 in “Georgetown Scientific Research Journal” This study found that intradermal bleomycin injections induced dermal fibrosis in C57BL/6 mice, evidenced by hair follicle obliteration and dermal thickening, though no significant trends in gene expression were observed, indicating the need for further research to understand the link between fibrosis and dyschromia.
May 2024 in “Anais brasileiros de dermatologia/Anais Brasileiros de Dermatologia” Oral minoxidil 7.5 mg for hair loss increases heart rate but not blood pressure.
October 2023 in “Journal of The American Academy of Dermatology” This article discusses the use of low-dose oral minoxidil as an off-label treatment for androgenetic alopecia but reports no new clinical results.
This study found that metformin treatment significantly decreased gremlin levels and improved insulin resistance in patients with polycystic ovary syndrome.
January 2023 in “Research Square (Research Square)” This study found that glycated proteins in untreated scalp hair may serve as a non-invasive marker for blood glucose control, but its applicability is limited by factors like cosmetic treatments and sample collection challenges.
March 2022 in “medRxiv (Cold Spring Harbor Laboratory)” This study found that individuals with blood type O had a higher risk of developing post-COVID-19 syndrome compared to non-O blood types.
January 2022 in “Dermatology Review” In this study, microneedling combined with bleomycin treatment for plantar warts improved the response time and reduced the number of treatment sessions needed, with a relapse rate similar to other injection-based methods.
January 2020 in “Nihon Yakuri Gakkai nenkai yoshishu” This study suggested that minoxidil's neuroprotective effect in mice was independent of its blood pressure-lowering action, unlike the effects observed with losartan and doxazosin.
May 2018 in “Pakistan journal of nutrition” This study found that feeding sheep rations with up to 30% Leucaena leucocephala leaf meal did not significantly affect mimosine concentrations or alter blood metabolites and thyroid hormones, suggesting it can be used without detrimental effects in these aspects.
April 2017 in “Journal of Investigative Dermatology” This study demonstrates that genome-edited epidermal stem cells can continuously monitor blood glucose levels in vivo and potentially aid in diabetes treatment through skin somatic gene therapy.
In this study, testosterone treatment was found to increase blood pressure in rats, potentially through mechanisms involving sodium and water retention in the kidneys and changes in specific gene expressions in the brain.
October 2013 in “Journal of the American College of Cardiology” Blood pressure that doesn't drop at night is linked to worse blood vessel function in people with high blood pressure.
January 2011 in “Hispania Judaica bulletin” This study found that mechanical and chemical interactions in skin organoids are crucial for initiating mesenchymal-epithelial interactions necessary for hair follicle regeneration.
January 2005 in “Linchuang pifuke zazhi” In this study, transfection of the VEGF165 gene increased hair growth and rejuvenated the atrophic dermis in a mouse model of sclerotic skin.
This study observed that hair follicle cycling in mouse skin involves physiological vascular remodeling, with VEGF playing a key role, suggesting potential therapeutic approaches for hair growth disorders.
August 2020 in “Benha Journal of Applied Sciences” This study found that patients with androgenetic alopecia had significantly higher mean platelet volume, neutrophil-to-lymphocyte ratio, and platelet-to-lymphocyte ratio compared to healthy controls.
March 2020 in “Journal of the turkish academy of dermatology” In this study, no significant difference was found in serum triglyceride and HDL cholesterol levels between male patients with androgenetic alopecia and those without.
February 2019 in “Journal of Pakistan Association of Dermatology” This study found that abnormal serum lipid levels were prevalent among male patients with androgenetic alopecia, with high triglycerides and low HDL observed frequently.
January 2018 in “International Journal of Medical Research and Health Sciences” This study found that prescribing finasteride for two weeks before TURP surgery reduces intraoperative and postoperative blood loss, the rate of blood transfusion, and irrigation fluid usage in patients with BPH.
August 2014 in “PLOS ONE” Hair loss is linked to eating less soy, having lower blood vanadium, and a specific genetic variation in Taiwanese communities.
February 2010 in “Journal of The American Academy of Dermatology” Women with androgenetic alopecia may have higher blood pressure levels.
116 citations
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August 2021 in “Stem Cell Research & Therapy” This paper reviews the emerging potential of menstrual blood-derived mesenchymal stem cell extracellular vesicles in regenerative medicine, highlighting their promise for treating several diseases without providing new clinical results.
53 citations
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July 2014 in “American Journal of Physiology-Endocrinology and Metabolism” This study found that testosterone-enanthate increased red blood cell production and altered iron homeostasis in older hypogonadal men without being affected by finasteride, indicating these effects do not require type II 5α-reductase enzyme activity.
48 citations
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September 2011 in “British Journal of Dermatology” This study found that DNA methylation and histone modification status were altered in peripheral blood mononuclear cells of patients with alopecia areata, suggesting these changes may contribute to the disease's pathological immune responses.
38 citations
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September 2004 in “Journal of Autoimmunity” Alopecia areata patients have more activated T cells in their blood, which may help in developing treatments.
34 citations
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July 2018 in “American Journal of Physiology-heart and Circulatory Physiology” Minoxidil improves blood flow and vessel flexibility, potentially helping with vascular stiffness.