Minoxidil Suppressed Cerebral Ischemic Injury by Direct Effect on Neural Tissues but Not by Reducing Blood Pressure

    January 2020 in “ Nihon Yakuri Gakkai nenkai yoshishu ”
    Hayasi Ryosuke, Yuki Honda, Hiroshi Hara, Toshihiko Kinoshita, Kyosuke Uno, Nobuyuki Kuramotoi
    Image of study
    TLDR Minoxidil protects brain tissue directly, not by lowering blood pressure.
    The study investigated whether minoxidil's neuroprotective effects in cerebral ischemia were due to its blood pressure-lowering properties or a direct effect on neural tissues. Using a transient ischemia model in C57/BL mice, researchers found that while minoxidil administration suppressed nerve tissue damage, a combination of losartan and doxazosin, which also lowered blood pressure, did not offer the same protection. This suggested that minoxidil's neuroprotective effect was independent of its ability to reduce blood pressure.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Is ketoconazole shampoo bullshit?

      in Ketoconazole  45 upvotes 2 years ago
      The conversation is about the effectiveness of ketoconazole shampoo for hair loss. The conclusion is that ketoconazole shampoo can help with dandruff and seborrheic dermatitis, but it is not a strong enough treatment to stop or regrow hair. It is recommended to use it as an adjunct treatment along with finasteride or dutasteride.

      community Just over 4 months in. Am I seeing things?

      in Is this regrowth?  37 upvotes 2 years ago
      The user reports potential hair regrowth after using finasteride nightly, minoxidil twice daily, occasional microneedling, and vitamin supplements, and is considering RU58841 in the future. Replies suggest they are seeing improvement.

      community Is it worth getting on oral minoxidil?

      in Minoxidil 2 years ago
      Evaluating the effectiveness of taking oral minoxidil as a hair loss treatment, in comparison to finasteride and topical minoxidil; discussing potential side effects of using oral minoxidil.

      community Why I deleted my YouTube channel Part I

      in Update  118 upvotes 4 years ago
      A YouTuber named Kevin, also known as Rider_Of_Roach, who deleted his YouTube channel due to personal attacks and controversy surrounding his views on hair loss treatments. He advocated for FDA-approved treatments like finasteride and minoxidil but faced backlash from those who disagreed with him. The conversation also discusses his past trolling behavior and a lawsuit he filed against a website that published false information about him. Despite some disagreements, many viewers appreciated his research-based content and hope to see him return in the future.

    Similar Research

    5 / 1000+ results