Blood Pressure Changes in Patients After Minoxidil Microinfusion to Treat Female Pattern Alopecia: Analysis of a Randomized, Single-Blinded, Placebo-Controlled Clinical Trial

    Flávia Machado Alves Basílio, Fabiane Mulinari‐Brenner, Betina Werner, Nayara Flores MACEDO

    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary This study found that microinfusion of minoxidil into the scalp was associated with a reduction in diastolic blood pressure, indicating systemic absorption of the drug.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 18

    1. Evaluation of Hair Regrowth After Minoxidil and Dutasteride Tattooing in Men with Androgenetic Alopecia JAAD international · 2023
    2. Female Pattern Hair Loss: Therapeutic Update Anais Brasileiros De Dermatologia · 2023
    3. Scalp Microinfusion: A Novel Drug Delivery Technique for Hair Loss Treatment Skin appendage disorders · 2023
    4. Low-Dose Oral Minoxidil for Alopecia: A Comprehensive Review Skin appendage disorders · 2023
    5. Efficacy and Safety of Scalp Microneedling in Male Pattern Hair Loss Skin appendage disorders · 2022
    6. Before-After Study With 24-Hour Ambulatory Blood Pressure Monitoring After the First Dose of 5 Mg Oral Minoxidil Journal of The American Academy of Dermatology · 2022
    7. Minimally Invasive Procedures for the Management of Female Pattern Hair Loss Journal of Cosmetic Dermatology · 2022
    8. Prospective Cardiovascular Evaluation with 24-Hour Holter and Ambulatory Blood Pressure Monitoring in Men Using 5-mg Oral Minoxidil for Androgenetic Alopecia Journal of The American Academy of Dermatology · 2022
    9. Minoxidil: A Comprehensive Review Journal of Dermatological Treatment · 2021
    10. Safety of Low-Dose Oral Minoxidil for Hair Loss: A Multicenter Study of 1404 Patients Journal of The American Academy of Dermatology · 2021
    11. How Much Medication Is Delivered in a Novel Drug Delivery Technique Using a Tattoo Machine? International Journal of Dermatology · 2019
    12. Microneedling for the Treatment of Hair Loss Journal of The European Academy of Dermatology and Venereology · 2017
    13. The Effectiveness of Treatments for Androgenetic Alopecia: A Systematic Review and Meta-Analysis Journal of The American Academy of Dermatology · 2017
    14. Androgenetic Alopecia: An Evidence-Based Treatment Update American Journal of Clinical Dermatology · 2014
    15. Minoxidil: Mechanisms of Action on Hair Growth British Journal of Dermatology · 2004
    16. Relationship Between Contact Time of Applied Dose and Percutaneous Absorption of Minoxidil From a Topical Solution Journal of Pharmaceutical Sciences · 1990
    17. The Pharmacokinetics of 2.5- to 10-mg Oral Doses of Minoxidil in Healthy Volunteers The Journal of Clinical Pharmacology · 1989
    18. Topical Minoxidil: Cardiac Effects in Bald Men British Journal of Clinical Pharmacology · 1988

    Related research 8

    1. Minoxidil Sulfotransferase Enzymatical Activity in Plants: A Novel Paradigm in Increasing Minoxidil Response in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2023
    2. Does Topical Minoxidil at Concentrations Higher Than 5% Provide Additional Clinical Benefit? Clinical and Experimental Dermatology · 2022
    3. Tretinoin Enhances Minoxidil Response in Androgenetic Alopecia Patients by Upregulating Follicular Sulfotransferase Enzymes Dermatologic Therapy · 2019
    4. The Use of Minoxidil in the Treatment of Male and Female Androgenetic Alopecia: A Story of More Than 30 Years Italian journal of dermatology and venereology · 2018
    5. Comparative Study Between 2% Minoxidil Topical Spray vs. Intradermal Injection for Treatment of Androgenetic Alopecia in Female Patients: A Controlled, 4-Month Randomized Trial 2010
    6. A Randomized Clinical Trial of 5% Topical Minoxidil Versus 2% Topical Minoxidil and Placebo in the Treatment of Androgenetic Alopecia in Men Journal of The American Academy of Dermatology · 2002
    7. Androgenetic Alopecia: Treatment Results with Topical Minoxidil Journal of The American Academy of Dermatology · 1987
    8. Topical Minoxidil Therapy and Hair Regrowth Archives of Dermatology · 1985