Mechanism and Clinical Efficacy of Peripheral Blood Alive Cell Treatment on Androgenic Alopecia

July 2024 in “ Chinese Medical Journal ”

Zigang Zhao, Xin Zhang, Xiaoyan Qu, Yaguang Zhou, Shui Yu, Q. Wang, Qian Zhang

peripheral blood alive cell treatment androgenic alopecia finasteride hair follicle cell proliferation Wnt/β-catenin signaling cell apoptosis blood circulation ACT AGA FNS

TLDR Peripheral blood alive cell treatment is effective and safe for treating hair loss.

The study investigated the efficacy and safety of peripheral blood alive cell treatment (ACT) for androgenic alopecia (AGA) in 60 male volunteers, divided into ACT and ACT + finasteride (FNS) groups. Both groups showed significant increases in hair counts after 6 months, with the ACT + FNS group showing improvements at both 3 and 6 months. The efficacy rates were 75.0% for ACT and 81.3% for ACT + FNS, with no significant difference between the groups. ACT was found to promote hair follicle cell proliferation, migration, and blood circulation, reduce cell apoptosis, and activate Wnt/β-catenin signaling. The treatments were effective and safe, showing promising clinical potential for AGA.

View this study on journals.lww.com →

Discuss this study in the Community →

Research cited in this study

3 / 3 results

research What's New in Therapy for Male Androgenetic Alopecia?

2 citations, September 2022 in “American Journal of Clinical Dermatology”

research Advances in Hair Growth

1 citations, January 2022 in “Faculty reviews”

The best long-lasting results in treating hair loss may be achieved through combination therapy, including treatments like finasteride, minoxidil, and platelet-rich plasma injections.

research Androgenetic Alopecia: A Review

153 citations, March 2017 in “Endocrine”

Male pattern baldness involves genetics, hormones, and needs better treatments.

Related Community Posts Join

6 / 38 results

community The Real Cause Of Androgenetic Alopecia

in Research/Science 669 upvotes 2 months ago

Androgenetic alopecia is caused by DHT affecting hair growth. Finasteride and minoxidil are used to manage hair loss by blocking DHT and promoting hair growth.

community I find it funny a bunch of us on here are on drugs for hairloss and maintain clean/healthy lives and then there’s these mf’s in the 90’s juiced to the gills with steroids and have better hair than all of us lol

in Satire 353 upvotes 1 year ago

The conversation is about the effects of steroids on hair loss. Some users believe that steroids can cause hair loss, while others argue that it depends on individual sensitivity to DHT. There is also discussion about the appearance of balding individuals who use steroids.

community How does dutasteride regrowth work?

in Finasteride/Dutasteride 6 upvotes 7 months ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

community Could low blood flow to the head cause an increased rate of thinning?

in Chat 27 upvotes 3 years ago

The user started using finasteride, minoxidil, and biotin for male pattern baldness (MPB) and is experiencing rapid thinning. They are questioning if low blood flow to the head could be contributing to their hair loss.

community Dental technician is convinced that he has found the cause of pattern hair loss

in Research/Science 317 upvotes 4 months ago

A dental technician claims malocclusion causes pattern hair loss due to poor scalp circulation. Users debate this, noting treatments like finasteride, minoxidil, and microneedling focus on DHT and blood flow.

community [25, F] [RANT] Shedding since March 2020. This just isn’t fair.

in Female 42 upvotes 3 years ago

User "missbloombastic" has been experiencing hair loss since 2016 and tried min, fin, multivitamins, and spiro with mixed results. Another user shares their struggle with hair loss and its impact on self-esteem, while a third user suggests checking blood tests and confirming the cause of hair loss.

Related Research

1 / 1 results

research Effectivity of Minoxidil as a Treatment for Alopecia Areata

January 2014 in “DOAJ (DOAJ: Directory of Open Access Journals)”

Minoxidil can effectively treat patchy hair loss by stimulating hair growth.