Mechanism and Clinical Efficacy of Peripheral Blood Alive Cell Treatment on Androgenic Alopecia

    July 2024 in “ Chinese Medical Journal
    Zigang Zhao, Xin Zhang, Xiaoyan Qu, Yaguang Zhou, Shui Yu, Q. Wang, Qian Zhang
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    Studysummary This study concluded that ACT injections, alone or combined with finasteride, have significant therapeutic effects and safety in treating androgenic alopecia, with promising clinical potential.
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    The study investigated the efficacy and safety of peripheral blood alive cell treatment (ACT) for androgenic alopecia (AGA) in 60 male volunteers, divided into ACT and ACT + finasteride (FNS) groups. Both groups showed significant increases in hair counts after 6 months, with the ACT + FNS group showing improvements at both 3 and 6 months. The efficacy rates were 75.0% for ACT and 81.3% for ACT + FNS, with no significant difference between the groups. ACT was found to promote hair follicle cell proliferation, migration, and blood circulation, reduce cell apoptosis, and activate Wnt/β-catenin signaling. The treatments were effective and safe, showing promising clinical potential for AGA.
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