Blood Group O and Post-COVID-19 Syndrome

    March 2022 in “ medRxiv (Cold Spring Harbor Laboratory) ”
    Sara Díaz-Salazar, Raquel Navas, Laura Sainz-Maza, Patricia Fierro, M. Maamar, Arancha Artime, Héctor Basterrechea, Benedetta Petitta, Carlota Lamadrid, Lucia Pedraja, Claudia Gandara-Samperio, Stefanie F. Pini, José M. Olmos, Carmen Ramos, Emilio Rodrigo, José L. Hernández
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    TLDR People with blood group O may have a higher risk of developing post-COVID-19 syndrome.
    The study "Blood group O and post-COVID-19 syndrome" conducted a case-control study on 121 subjects who had experienced mild COVID-19 to assess the association between blood group O and post-COVID-19 syndrome (PCS). The study found that blood group O was associated with a 4-fold increased risk of PCS compared to non-O blood groups (adjusted OR=4.20 [95%CI, 1.2-14]; p=0.023). In addition, O-group PCS+ patients had significantly higher lymphocyte count, higher levels of fibrinogen and CRP, and higher percentages of 3 composite indices, than PCS- subjects. These findings suggest that blood group O may be a risk factor for developing PCS after a mild COVID-19 infection.
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