Small Extracellular Vesicles from Menstrual Blood-Derived Mesenchymal Stem Cells as a Novel Therapeutic Impetus in Regenerative Medicine

    August 2021 in “ Stem Cell Research & Therapy ”
    Lijun Chen, Jingjing Qu, Quanhui Mei, Xin Chen, Yangxin Fang, Lu Chen, Yifei Li, Charlie Xiang
    Studysummary This paper reviews the emerging potential of menstrual blood-derived mesenchymal stem cell extracellular vesicles in regenerative medicine, highlighting their promise for treating several diseases without providing new clinical results. Our plain-language summary of this paper — not a Tressless recommendation.
    The document discussed the potential of small extracellular vesicles (EVs) derived from menstrual blood-derived mesenchymal stem cells (MenSCs) in regenerative medicine. Although research on MenSC-derived small EVs was in its early stages compared to other mesenchymal stem cell sources, the study highlighted their promising therapeutic effects in various conditions, including fulminant hepatic failure, myocardial infarction, pulmonary fibrosis, prostate cancer, cutaneous wounds, type-1 diabetes mellitus, and aged fertility. The document emphasized the rapid advancements in understanding the therapeutic potential of MenSC EVs and proposed new areas for research to address existing challenges, suggesting that MenSC EV-based treatments could become a novel strategy in regenerative medicine.
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