Effects of 5-Alpha-Reductase Inhibitor (Finasteride) on Perioperative Blood Loss in Patients with BPH Undergoing TURP

    January 2018 in “ International Journal of Medical Research and Health Sciences ”
    Sherwan Mohammed Amin, Shawqi Goerge Ghazala, Nihad Rafaat Jawad
    TLDR Finasteride reduces blood loss and the need for blood transfusions during and after TURP surgery.
    The study assessed the effects of finasteride on blood loss in patients with BPH undergoing TURP. Fifty patients were divided into two groups: one received finasteride for two weeks before surgery, and the other did not. Results showed that the finasteride group had significantly less postoperative hemoglobin drop, lower blood transfusion rates (1% vs. 7%), and reduced use and duration of irrigation fluid compared to the control group. The conclusion was that finasteride reduced intraoperative and postoperative blood loss, blood transfusion rates, and the need for irrigation fluid in these patients.
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